518, 3645–3661. molyneaux, b.j., goff, l.a., brettler, a.c., chen, h.h., hrvatin, s., rinn, j.l., and arlotta, p. (2015). decon: genome-wide analysis of in vivo transcriptional dynamics during

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Answer 1

To achieve distinct cellular identities during neuronal development, a complicated dance of transcriptional choices is needed.

A genome-wide investigation of the kinetics of in vivo transcription during the neocortical selection of pyramidal neuronThe immense complexity in time and space during development has made it difficult to achieve the ultimate objective of identifying genome-wide markers that define and drive specific neuronal destinies.In order to clarify lineage choice decisions, we have combined high-throughput purification of pyramidal neuron subclasses with in-depth tracking of spatiotemporal transcriptional dynamics during corticogenesis. We discovered a variety of characteristics, from the use of different mRNA isoforms and promoters in space and time to a large number of mRNA genes that are altered during fate specification. Notably, we found a large number of long non-coding RNAs that expressed only under specified conditions and in certain cell types. We offer an interactive online database that enables multidimensional data processing and dissemination in order to aid future exploration. This comprehensive work creates a valuable resource and advances knowledge of the transcriptional control that underlies pyramidal neuron diversity in the neocortex.

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the question you are looking for is

DeCoN: genome-wide analysis of in vivo transcriptional dynamics during pyramidal neuron fate selection in neocortex


Related Questions

march the chemic reaction with its correct type

Answers

Answer:

1. A

2. C

3. D

4. B

Explanation:

find these types of reactions online, my explanation wouldnt be great

sometimes you hear that only a small minority of different bacterial species cause diseases in humans or animals. are there reasons for thinking that this might not be true.

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The proposed idea is true. This is because:

The human body is a sophisticated ecology that is prospering. In addition to human cells, it also contains bacterial, fungal, and protozoan cells, which comprise thousands of microbial species. These microorganisms, also known as the normal flora, are typically restricted to particular body parts, such as the skin, mouth, large intestine, and vagina. Humans are also constantly infected with viruses, the majority of which just sometimes or never cause symptoms.Typically, pathogens are distinct from the native flora. Only when our immune systems are compromised or when they get access to a typically sterile area of the body do our normal microbial residents cause problems.For example, a perforation in the bowels might enable the native gut flora to enter the peritoneal cavity resulting in peritonitis.Dedicated pathogens, on the other hand, don't need the host to be hurt or have their immune system impaired. They have created highly sophisticated methods for overcoming cellular and biochemical barriers and for inducing particular reactions in the host organism that aid in the pathogen's survival and growth.

So, some pathogens might make humans and animals sick.

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list the similarites between amino acids, fatty acids, and sugars(monosaccharides).

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The similarities between amino acids, fatty acids, and sugars include the following below:

They are organic compounds.They are formed by the digestion of food. Some of them can be produced by the body.

What is a Biomolecule?

This is referred to as a  biological molecule and are substances which are produced by cells and living organisms. Examples include the following:

CarbohydrateNucleic acidFatty acid etc

They all contain carbon atoms present in their molecular structure which is why they are referred to as organic compounds and can be produced by the body through some metabolic reactions.

Food substances serves as a source for these biomolecules as they are usually broken down through enzymatic actions in the process referred to as digestion.

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what is heterogeneous

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diverse in character or content
there are different means for this word like:

{-} diverse in character or content.

Chemistry:
{-} of or denoting a process involving substance in different phases (solid, liquid, or gaseous).

Mathematics:
{-} incommensurable through being of different kinds, degrees, or dimensions.

theses are the three main meanings

Hopes this helps!!!

there are three swellings that occur at the anterior end of a fluid-filled tube in the developing embryo. these three swellings eventually develop into the adult:

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There are three swellings that occur at the anterior end of a fluid-filled tube in the developing embryo. these three swellings eventually develop into the adult: forebrain, midbrain, and hindbrain.

The forebrain, midbrain, and hindbrain are three primary components of the brain.

These three components differ in structure and functions respectively.

Forebrain accounts for 2/3rd of the interior of the brain and is composed of thalamus, hypothalamus and cerebrum. Its main function is sensory procession, however, it is also responsible for dinking, eating, emotional display and body temperature.

Midbrain is located in the center of forebrain and hindbrain and is responsible for movement, and also controls visual and auditory information.

Hindbrain is connected to spinal cord and helps in the cardiovascular reflexes, and coordination of motion.

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Nitrogen is also cycled through living organisims

True or False

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Answer:

True, death and decay of dead animals and also excretion cycles nitrogen

The interference pattern seen when light passes through narrow, closely spaced slits, is due to.

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The interference pattern seen when light passes through narrow, closely spaced slits, is due to Diffraction:

Diffraction is a light phenomenon that occurs when light strikes an impediment or travels through the slit. This results in a light pattern known as interference.

When light goes through a slit or hits an object, it creates a series of patterns known as interference patterns. The light bends through the corners of the barriers or passes through a slit that might behave as an obstruction. The pattern is caused by the diffraction phenomenon and involves the form of the slit in it. Diffraction is the sole phenomena that causes interference patterns, rather than reflection, refraction, dispersion, or deflection. Thomas Young's work on limited double-slit geometry produced observable interference effects and was the basis for diffraction.

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fungi question 17 options: 1) absorb nutrients from the environment. 2) take in food by phagocytosis. 3) generate atp and reducing equivalents by photosynthesis.

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D.) Fungi absorb nutrients from the environment.

Fungi- Fungi can be either single-celled creatures or extremely complex multicellular ones. Although they can be found practically anywhere, most of species prefer to reside on land, primarily in dirt or on plant materials, as compared to the ocean or fresh water. The decomposers, a class of organisms that grow in the dirt or on decomposing plant matter, have a substantial impact just on cycling of carbon and other substances.

Organism- An organism is a collection of molecules working together to form a more or less stable whole that demonstrates the characteristics of life.

The given question is incomplete, please find below the complete question,

Q. Fungi ________.

A) Absorb nutrients from the environment

B) Take in food by phagocytosis

C) Generate ATP and reducing equivalents by photosynthesis

D) All of the choices are correct.

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The Ribosome is to protein as the Nucleolus is to _______________________. Group of answer choices Lysosome Energy Glucose Ribosome

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Ribosome is the correct answer

Answer:

Ribosomes are involved in protein synthesis. Almost all enzymes are proteins. Hence, ribosomes make enzymes too. Chemical structure of hormones is diverse including steroid, eicosanoids, amino acids derivatives, proteins and peptides. Hence, except proteinous hormones, all other types of hormones cannot be synthesized by ribosomes.Ribosomes are not involved in starch manufacture.Was this answer helpful?

Glucose is a large molecule that needs help entering a cell. Which is the most likelypathway glucose will take to enter the cell?.

Answers

Answer:

-=-=-=--==--=-=-=-==-=---=-=-=-

Explanation:

{}{}{}{}{}{}{}{}{}{}{}{}

Enzymes act as_______________ in the body and help ______________ the metabolic processes within the cell. locks, slow down immune factors, protect chemical catalyst, speed up gatekeepers, monitor

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Enzymes act as organic catalyst in the body and help in the speed up the metabolic processes within the cell.

Enzymes- An enzyme is a type of biological catalyst that is typically always a protein. It quickens a certain chemical reaction inside the cell. Throughout the procedure, the enzyme is continually used and is not lost.

Amylase, for instance, supports the transformation of carbs into sugars in saliva.

Metabolic Process- Metabolic activities in the body's cells that turn food into energy are referred to as metabolism. Our bodies need this energy in order to move, think, and develop. Specific proteins in the body control the chemical reactions involved in metabolism.

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The ossicles are the three smallest bones in the human body. please select the best answer from the choices provided t f

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The given statement is true that the ear ossicles are the three smallest bones in the human body.

Ossicles, also called auditory ossicles, one of the three small bones in the middle ear of all mammals. These are the hammer or the malleus, the incus or the anvil and the stapes or stirrup. Together they form a short chain that passes through the middle ear and transmits vibrations caused by sound waves from the tympanic membrane to the fluid in the inner ear. The malleus looks more like a club than a hammer, while the anvil looks like a premolar with an extensive root system. The stapes looks a lot like a stirrup. The top or head of the hammer and the body of the anvil are held together by a tight connection and are located in the attic, or top, of the tympanic cavity. The hammer handle attaches to the upper half of the drum diaphragm.

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then drag the labels of group 2 to their respective targets to identify how o2 and co2 cycle in the ecosystem.

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Photosynthesis is the process in which green plants utilize sunlight, water and carbon dioxide to produce oxygen and energy in the form of sugar.

Photosynthesis occurs in the chloroplasts and has two reactions, namely the light-dependent and the light-independent reactions.

In the light-dependent or light reaction of photosynthesis, solar or light energy is converted to chemical energy in the thylakoids and during this process ATP and NADPH are produced and [tex]O_2[/tex] is released.

During the light-independent or dark reaction of photosynthesis, also known as the Calvin cycle, the ATP provides energy for synthesis of sugar whereas the NADPH provides the electrons for the reduction of [tex]CO_2[/tex] into glucose.

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Which is a function of the lymphatic system?
regulating hormones
maintaining body temperature
maintaining fluid balance
distributing oxygen

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Explanation:

Which is a function of the lymphatic system?

Maintaining fluid balance...

[tex]...[/tex]

The coperican model of the solar system was a ____ model in which Earth_____ . Planets _____ and the stars____.

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Answer:

was a heliocentric,  Earth was just another planet, Planets travelled along a circular path,  stars floated in outer space.

Explanation:

what are three ways that form ores​

Answers

There are 3 predominant varieties of ore genesis: inner approaches, hydrothermal strategies, and surficial methods. Ore can accumulate through geologic hobby, such as when volcanoes deliver ore from deep inside the planet to the floor. this is known as an inner system.

Ores are classified based totally on how they shape. a few ores form from the cooling and crystallization of minerals inside magmas, lavas, or igneous intrusions. these are called magmatic or volcanic ores. Nickel, copper, and iron ores are usually fashioned from magmatic or volcanic-related deposits.

Gold minerals form in hot rocks in and around volcanoes. Low sulfur, gold-bearing hydrothermal fluids shape while hot rocks warmness ground water. An instance of those low-sulfur fluids are hot springs like those at Yellowstone country wide Park. The ores of round Mountain, Nevada, are usual low-sulfur deposits.

An ore is a rock that carries sufficient of a metallic or a steel compound to make extracting the steel worthwhile: low-grade ores include a small percent of the metallic or its compound. high-grade ores include a bigger percentage.

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What do you notice is the main difference between the structure of the connective tissues and the structure of the epithelium? make sure to note the organization of cells in these two tissue types. How does this structure relate to function?.

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Epithelial tissue lines the cavities and surfaces of organs and blood arteries throughout the animal body, whereas connective tissue supports, links, and divides many types of tissues and organs in the body. This is the main distinction between epithelial and connective tissue.

Cell arrangement: The physical properties of the Epithelial tissue affect how the connective tissue is organized. There are different arrangements of epithelial cells, such as squamous, cuboidal, and columnar, that organize as simple, stratified, pseudostratified, and transitional. Since epithelial cells form from ectoderm, mesoderm, and endoderm, this explains why epithelia line body cavities. Dense irregular connecting tissue is made up of messily organized tightly packed collagen bundles.

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rotein synthesis is an essential part of cellular metabolism, and it requires the involvement of a number of molecules, structures, and organelles. list the molecules, structures, and organelles in the order that enables protein synthesis. start with the instructions that encode a protein, and end with the structure through which a protein leaves the cell.

Answers

According to the given statement the correct order is

DNA ⇒ RNA ⇒ Ribosomes ⇒ Endocytic reticulum in rough ⇒ Golgi apparatusPlasma layer  ⇒ Protein Leaves the Cell

What is Ribosome?

At a ribosome, an intercellular structure made of both RNA and protein, the process of making proteins happens in a cell. The messenger RNA (mRNA) sequence is processed by the ribosome, which translates the gene sequence into a specific string of amino acids that form extended chains and fold to make proteins.

What roles do ribosomes function?

Ribosomes' two major purposes are peptide bond formation and message decoding. These two tasks are carried out by the two large, unequal-sized ribonucleoprotein particles (RNPs) called as the ribosomal subunits. A variety of ribosomal proteins and one or more ribosomal RNAs (rRNAs) make up each subunit (r-proteins)

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a simple three-item questionnaire and psa level can help distinguish luts secondary to bph vs those with other causes7

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Benign prostatic hyperplasia  is a complex disease that is progressive in many men.

Benign prostatic hyperplasia  is regularly associated with symptoms of the lower urinary tract, acute urinary retention (AUR), and BPH-related surgery are some of the complications of such a disease. It is necessary to fo the men identify the increased risk of Benign prostatic hyperplasia procession to optimize therapy. Many factors are involved in a such progression such as prostate volume, age, and so on. Serum prostate-specific antigen level is correlated to prostate volume, which makes it easy to determine the risk of the progression. For Benign prostatic hyperplasia, medical treatments are mostly used treatment. Alpha-blockers grabbed the instant symptom relief but didn't reduce the risk of Benign prostatic hyperplasia surgery. the 5-alpha-reductase inhibitors affect the disease and reduced the prostate volume, which leads to improved symptoms and reduced the risk of  Benign prostatic hyperplasia surgery and AUR. Combination therapy is more beneficial than monotherapy,  there were the result of symptom improvement  with such  therapy  

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A type of membrane protein that is integrated into the hydrophobic region of the membrane.

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Integral membrane proteins are integrated into the hydrophobic region of the membrane.

Integral membrane proteins are kind of proteins which has particular functional regions and are inserted into the plasma membrane.

This membrane has a hydrophobic region that helps them to get attached to the hydrophobic central part of the phospholipid bilayer.

In many organisms, these comprise large portions of the genome.

Transmembrane proteins are categorized as integral membrane proteins but not all IMPs are TMPs.

To put it simply, these membranes are found around organelles and cells and help out in the movement of molecules or fluids across them.

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which statement best describes the difference between the sympathetic and parasympathetic nervous systems?

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Answer:So the answer that correctly defines these two systems is (A). The sympathetic nervous system prepares the body for strenuous activity and the fight-or-flight response, whereas the parasympathetic nervous system conserves energy and regulates the rest-and-digest state.

Explanation:

Which of the following represents arrow B? ( Look at Photo )

A. Carbon Dioxide
B. Glucose
C. Oxygen
D. Blood Vessel (capillary)

Answers

if its select all that apply A and C if no its C

effects of preservatives in pitfall traps for collecting arthropods: a comparison of ethylene glycol and five alternative preservatives

Answers

To study arthropods in forests, pitfall traps with ethylene glycol as a preservative are frequently employed.

What does the study of pitfall traps for collecting arthropods indicate?Because ethylene glycol is sweet, there have recently been reports of wild vertebrates damaging pitfall traps. In order to choose an alternate preservative for use in pitfall traps, this study evaluated ethylene glycol with five viable substitutes. The study employed the five substitute preservatives. Depending on the type of preservative employed, different numbers of arthropods were gathered, and distinct arthropod assemblages had varying compositions. The later of the two alternate preservative combinations that were shown to be more effective for collecting arachnids, formalin+bleach and salt water+bleach.

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ldentification of a disease resistance locus in arabidopsis that is functionally homologous to the rpg7 locus of soybean

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It was identified that a disease resistance locus in Arabidopsis is functionally homologous to the rpg1 locus of soyabean.

How was disease resistant locus identified in Arabidopsis?

Using an avirulence gene that was previously cloned from a pathogen that does not affect Arabidopsis, the new disease resistance locus RPS3 in that plant was discovered. Pseudomonas syringae pv. tomato strain that is virulent on Arabidopsis was transformed with the avrB avirulence gene from the soybean pathogen, and conversion to avirulence was tested on Arabidopsis plants. On most Arabidopsis ecotypes, but not all, the avrB gene was avirulence active. Of the 53 ecotypes that were tested, eight were susceptible and 45 were resistant to a P. syringae pv. tomato strain that carried avrB. Crosses between the susceptible ecotype Bla-2 and the resistant ecotype Col-0 were used to study the transmission of this resistance. The ratio of resistant to susceptible F2 plants from this cross was almost 3:1, showing that ecotype Col-0's solitary dominant locus, RPS3, controls resistance to P. syringae that expresses avrB. RPS3 was located on chromosome 3 near markers M583 and G4523 and or = 1 cM from RPM1, another disease resistance locus, using RFLP analysis. The locus RPG1 in soybean regulates resistance to P. syringae strains that possess avrB. As a result, RPG1 and RPS3 both provide resistance to avrB-specific diseases, raising the possibility that these genes are homologs.

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The correct question is Identification of a disease resistance locus in Arabidopsis that is functionally homologous to the RPG1 locus of soybean

Please Help due soon.

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Explanation:

marshes and swamps.

answer

Which two sentences taken together provide the
BEST evidence to support the idea that many
nutritious alternatives exist within each of the food
groups?

Answers

The five food groups include:

Starchy foodFruit and vegetablesProteinDairyFatFoods are combined into groups because they offer comparable levels of the essential elements found in that food group. For instance, calcium and protein are important elements for the food group that consists of milk, yoghurt, cheese, and substitutes, but the fruit category is a strong source of vitamins, particularly vitamin C.You must consume a variety of foods from each of the five food categories every day in the prescribed amounts if you want to consume the recommended levels of nutrients to maintain excellent health.Additionally, it's crucial to eat a variety of meals from each of the Five Food Groups because different foods contain different amounts of the essential elements.For instance, the vitamin A content of orange vegetables like carrots and pumpkin is much higher than that of other vegetables like white potatoes in the food group of vegetables and legumes.

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if phosphorous concentrations were to suddenly increase in a marine ecosystem, which of the choices would likely occur?

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If phosphorus concentrations suddenly increased in a marine ecosystem, then primary productivity will also increase.

Ecosystem A biotic community along with its abiotic environment  together form an ecological system or ecosystem. Tansley introduced the term "ecosystem" in 1935.An ecosystem is a self-regulating, self-sustaining structure that serves as a functional unit of the biosphere. It is made up of a community of living things and their physical surroundings, and it is this community that interacts and exchanges materials.The essential functions of ecosystem function include:productivitydecompositionenergy flownutrient cyclingProductivity:

It is defined as the rate of biomass production.

Primary productivity:

It is referred to as the quantity of biomass or organic matter created by plants during photosynthesis per unit of area over time.

It is divided into:

Gross primary productivity Net primary productivity.

Hence, the correct answer is that the primary productivity increases.

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a deadly embrace: hemagglutination mediated by sars-cov-2 spike protein at its 22 n-glycosylation sites, red blood cell surface sialoglycoproteins

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A Deadly Embrace: Hemagglutination Mediated by SARS-CoV-2 Spike Protein at Its 22 N-Glycosylation Sites, Red Blood Cell Surface Sialoglycoproteins, and Antibody is a research paper by David E. Scheim.

What is the abstract?

The characteristics of various enveloped virus strains dating back to foundational results from the 1940s are highlighted by rouleaux, or stacked clusters, of red blood cells (RBCs), which were found in the blood of COVID-19 patients in three studies. The following are important examples for COVID-19: Although ACE2 is the target for SARS-viral CoV-2's fusion and replication, SARS-CoV-2 initially attaches to sialic acid (SA) terminal moieties on host cell membranes via glycans on its spike protein; however, hemagglutinin esterase (HE), an enzyme that releases these glycan-mediated bindings to host cells, is expressed among betacoronaviruses in the common cold strains but not by SARS-CoV, SARS-CoV-2 and MERS.

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anaphylaxis caused by stinging insects is typically an allergic reaction to rather than the bite or sting itself.

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Anaphylaxis caused by stinging insects is typically an allergic reaction to the injected poison, irritating toxin, and deadly venom rather than the bite or sting itself. The correct answer is option(D)i.e, All of these answers are correct.

Anaphylaxis can be fatal if untreated or improperly treated. Even if your symptoms disappear pretty quickly, they may return a few hours later, worsen, and become more challenging to cure.

People who have allergies typically experience mild to moderate symptoms, such as watery eyes, a runny nose, or a rash. Anaphylaxis, a serious allergic reaction that can be fatal, can however occasionally result from exposure to an allergen. When too many chemicals are released at once, shock results, which is a severe reaction

The most frequent triggers within these groups were wasp and bee stings (n = 1460 and 412, respectively), legumes (n = 241), animal proteins (n = 225), and analgesics (n = 277). In children, peanuts, cow milk, and hen's eggs were the most common food allergens to cause anaphylaxis; in adults, it was wheat and shellfish. When you have anaphylaxis, your immune system releases a rush of chemicals that can put you in shock and cause your blood pressure to drop and your airways to constrict.

The complete question is:

Anaphylaxis caused by stinging insects is typically an allergic reaction to ____________ rather than the bite or sting itself.

A. injected poison

B. irritating toxin

C. deadly venom

D. All of these answers are correct

what is luster?? need help please

Answers

Gentle sheen or dark glow
Other Questions
which term describes aristotle's opinion on knowing the different types of government? pointless pointless unnecessary unnecessary critical critical impossible 6.(11x-47)(6x-2)m1Solve for missing variable l and m are parallel In right triangle $ABC,$ $\angle C = 90^\circ.$ Median $\overline{AM}$ has a length of $19,$ and median $\overline{BN}$ has a length of $18.$ What is the length of the hypotenuse of the triangle? what is the value of (x+y)^2 when x=2 and y= -4? 2x2+2x28161418HELP ME PLS you are stinky . i hope you know tht which protects tricare beneficiaries from devastating financial loss due to serious illness or long-term treatment by establishing limits over which payment is not required? Which of the following statements about white space is NOT TRUE?A. It doesn't alway have to be white.B. It is not usefulC. It makes reading easier for the readerD. It can be located between paragraphs and pictures Which detail from the text lets the reader know that this story takes place in thefuture?Margot lives on VenusRain falls for seven years straightScientists study the sunChildren dream of the sun ldentification of a disease resistance locus in arabidopsis that is functionally homologous to the rpg7 locus of soybean Given mn, find the value of x.20X List examples of specific roles that the us government plays in the operation of the economy. Describe the inside of the houses that Mac and Dennis enter after leaving the ranch. Include at least two details from the story. What is the primary tool psychologists use to answer questions about behavior and thinking?. the volume of the atlantic ocean is about 3.1 \cdot 10^{17}3.110 17 3, point, 1, dot, 10, start superscript, 17, end superscript cubic meters. the mississippi river has an annual flow of 6.3 \cdot 10^{11}6.310 11 6, point, 3, dot, 10, start superscript, 11, end superscript cubic meters. how many times would the annual flow of the mississippi river fit in the atlantic ocean? what can the reader infer about the monk's character based on the fact that all of his stories contain the same tragic moral? a. he is a simple person that only sees the world in absolutes. b. he does not know stories outside of the biblical ones. Solve the following integers In the bicarbonate buffering system, carbon dioxide and water join to form ___________, which dissociates into hydrogen and ________________. HELP PLEASE ASAP!!!! Where on the periodic table do you find elements that have 'full' valence electron shells and are thus stable and unreactive? (1 pt)*1 pointon the left side of the periodic tableon the right side of the periodic tableacross the top of the periodic tableacross the bottom of the periodic tablein the middle of the periodic tablescattered around the periodic table