61. casares, d.; escribá, p. v.; rosselló, c. a., membrane lipid composition: effect on membrane and organelle structure, function and compartmentalization and therapeutic avenues. int j mol sci 2019, 20 (9).

Answers

Answer 1

Biological membranes are essential components for the upkeep of cell physiology and architecture.

What is the role of biological membrane?Beyond serving as a simple barrier to keep the cell's inside from its exterior, the plasma membrane also initiates intracellular signals, acts as a framework for cell-to-cell communication, and has additional purposes. The compartmentalization of the plasma membrane into lipid microdomains, which regulates the location and beneficial interactions of proteins involved in the transmission of cell signals, is essential for this function. In addition, additional membranes that are tightly regulated in terms of integrity and homeostasis and that govern the identity and function of the many organelles split cells into compartments.

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Related Questions

characteriza-tion of a 50-kda polypeptide in cytoplasmicdynein preparations reveals a complex withp150gluedand a novel actin.

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hCaracteriza-tion of a 50-kda polypeptide in cytoplasmicdynein preparations reveals a complex withp150gluedand a novel actin

a group of auxiliary polypeptides with molecular hundreds of a hundred and fifty, seventy four, 59, 57, 55, 53, 50, and 45 kDa have been determined to copurify with cytoplasmic dynein. in the modern-day observe, a specific monoclonal antibody used to immunoprecipitate the 50-kDa polypeptide from the cytosol of the bovine mind discovered coprecipitating additives of 150, a hundred thirty five, 62, and forty five kDa that had been fully distinct from the polypeptides immunoprecipitated with an antibody to the  74-kDa cytoplasmic dynein subunit. The mammalian equivalent of the Drosophila Glued gene, p150Glued, became reactive with the one hundred fifty- and a hundred thirty five-kDa polypeptides. The primary forty five-kDa aspect of the complicated was identified as the alpha-isoform of contractin, a new form of actin, with the aid of N-terminal microsequencing of tryptic peptides. while contractin, p50, and p150Glued have been immunoblotted from sucrose gradient-fractionated mind cytosol, they have been determined to cosediment entirely at 20 S. using an antibody to p150Glued, immunofluorescence microscopy confirmed centrosomal staining, which microtubule depolymerization eliminated. these findings put together display that the 50-kDa polypeptide is part of a cytosolic complicated that is unique from cytoplasmic dynein. but according to the immunolocalization information, there may be a connection to microtubule minus ends, which raises the possibility of cellular-dynein touch.

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all other factors (concentration, solute size, etc.) being equal, which type of solute does a cell tend to pull inside?

Answers

Answer: Positively-charged solutes

Explanation:

The excess of negative charge on the cytosolic side of the plasma membrane tends to pull positively charged solutes into the cell. Specifically, a variety of negatively charged inorganic and organic ions (anions), including nucleic acids, proteins, and many cell metabolites, maintain this relatively constant "positive pull" at the surface of the cell.

How are osmosis and diffusion different? Select all that apply.

1: With osmosis, solutes cross the semipermeable membrane. With diffusion, water moves across the membrane
2: With osmosis, water crosses the semipermeable membrane. With diffusion, solutes move across the membrane.
3: Both osmosis and diffusion move from areas of high concentration to low concentration
4: Both osmosis and diffusion move from areas of low concentration to high concentration

Answers

Answer: 3- Both osmosis and diffusion move from areas of high concentration to low concentration

In diffusion, there is no membrane involved.

That's why 1 and 2 don't count.

Diffusion and osmosis move from an are of high concentration to low concentration, not low to high, that's why 4 doesn't count either.

hope it helps.

if a molecule is too big to move in or out of a cell on its own, but uses a protein channel to move, without additional energy, what type of transport is this?

Answers

Facilitated transport is the type of transport way which does require protein channel but not any ATP (energy).

Facilitated Transport- Facilitated transport is one way to move such materials without utilizing cellular energy. During assisted transport, materials are traveling down a concentration gradient. They are, in other words, passively diffusing from an area of high concentration to an area of low concentration.

Without the use of energy, chemicals simply migrate passively from a region of higher concentration to a region of lower concentration.

Example, A case of facilitated diffusion is glucose transfer.

ATP- Basic Unit of Energy Molecule to perform any function

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What roles do membrane proteins play in transporting only certain substances into a cell.

Answers

Some let the passage of only certain molecules, even when the concentration gradient is present. Some operate as a one-way control. Others allowed a lot of things to happen.

Membrane protein

A membrane protein is a protein molecule that is joined to or connected to an organelle's or cell's membrane.

Depending on how the protein is connected to the membrane, membrane proteins can be divided into two categories.

The plasma membrane contains integral membrane proteins that are permanently ensconced there.

On both the inside and outside of membranes, peripheral membrane proteins can be found, often bound to phospholipids or integral proteins.

What roles do membrane proteins play?

Membrane proteins provide a variety of crucial tasks that aid in cell communication, shape maintenance, carrying out changes brought on by chemical messengers, and material transport and sharing.

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One primary advantage of light microscopy over electron microscopy is that ________.

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One primary advantage of light microscopy over electron microscopy is that light microscope can be used to view live specimens.

What is light microscopy?

Light microscopy is the scientific instrument which provides a magnified view of very small objects that are illuminated with visible light which then passes through optical lenses.

On the other hand, the electron microscope is any of theseveral forms of microscope that use a beam of electrons, rather than one of light, and thus has a much greater resolving power.

The electron microscope is known to be way better at viewing structures than the light microscope. However, one major downside of the electron microscope is that it cannot be used to view live specimens unlike the light microscope.

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An atom of a certain element has 36 proton,36 electrons and a mass number of 84.at room temperature this element is a very stable gas.how many neutrons are in this atom

Answers

Answer:

b^2+c^2+a^2 pretty easy

where is most of the water in the body located? where is most of the water in the body located? intracellular fluid lumens of the digestive and urinary tracts interstitial fluid plasma

Answers

Most of the water in the body is stored in intracellular fluid.

Water :

Water is the largest component of water. It makes up 60 % of the body. It is an essential nutrient that is present in plants and animals. Water forms several functions that are essential to life.

Water in the body is distributed the inside the body. It is present in the cells. The intracellular fluid protects the cell in the body. It maintains the temperature and pH of the cells.

Most of the water enters the body while drinking the water. The water present in the digestive and urinary tract is the two/third part of the cells.

The water makes the cells hydrated and maintains osmolarity in the cells. Glucose, sodium ions and some inorganic ions are present in intracellular fluid.

Therefore, most of the water in the body is stored in intracellular fluid.

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a cell has 6 pairs of homologous chromosomes. following mitosis and cytokinesis how many chromosomes will each daughter cell contain? chegg

Answers

if the cell has 6 pairs of homologous chromosomes. following the mitosis and cytokinesis the result are Each daughter cell will have the half of the original 46 chromosomes, or the 23 chromosomes. Each chromosome has consists of 2 sister chromatids.

The Homologous Chromosomes are made of the chromosomal pairs of the same length and the centromere positions for the genes which corresponding to the same loci. Typically one of the most chromosomes is inherited by from the father and to the other from the mother. Diploid organisms, like the humans, that carry two copies of the genome in each of one of their cells. Having two copies of the each chromosome, called as homologous chromosomes, which helps increase the both the variety and the stability of a species

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transcription factor irf4 promotes cd8( ) t cell exhaustion and limits the development of memory-like t cells during chronic infection.

Answers

Chronic stimulation results in an exhausted phenotype in CD8+ T lymphocytes that is defined by the production of inhibitory receptors, down-modulation of effector function, and metabolic abnormalities. T cell fatigue restricts the removal of virus-infected or tumour cells but protects against severe immunopathology.

What is Transcription factor ?

A transcription factor is a molecule that regulates a gene's function by deciding whether its DNA (deoxyribonucleic acid) is converted into RNA (ribonucleic acid). Using the DNA of the gene as a template, the enzyme RNA polymerase catalyses the chemical processes that result in the synthesis of RNA.

The SRY protein is another illustration of a transcription factor that participates in development. For sex differentiation to occur during human development, the SRY protein is required. The SRY protein activates genes involved in the development of the male reproductive system.

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The nerves that make up the spinal cord carry commands between the __________ and the brain.

Answers

Answer: Peripheral nerves

Explanation:

vander’s human physiology, 15th ed. by eric widmaier, hershel raff, kevin strang publisher: mcgraw hill online pdf

Answers

Vander’s human physiology, 15th ed. by eric widmaier, hershel raff, kevin strang publisher: mcgraw hill is a textbook on human physiology easily available on amazon or flipkart. You can also try to find this book in online free libraries.

What are the contents in the book?Chapter 1 Homeostasis: A Framework for Human PhysiologyChapter 2 Chemical Composition of the BodyChapter 3 Cellular structure, proteins, and MetabolismChapter 4 Movement of Molecules Across Cell MembranesChapter 5 Control of Cells by Chemical MessengersChapter 6 Neuronal Signaling and the Structure of the Nervous SystemChapter 7 Sensory PhysiologyChapter 8 Consciousness, the Brain, and BehaviorChapter 9 MuscleChapter 10 Control of Body MovementChapter 11 The Endocrine SystemChapter 12 Cardiovascular PhysiologyChapter 13 Respiratory PhysiologyChapter 14 The Kidneys and Regulation of Water and Inorganic IonsChapter 15 The Digestion and Absorption of FoodChapter 16 Regulation of Organic Metabolism and Energy BalanceChapter 17 ReproductionChapter 18 Defense Mechanisms of the BodyChapter 19 Medical Physiology: Integration Using Clinical Cases

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evaluation of the respective influence of thyroid hormonesand tsh on blood coagulation parameters after total thyroidec-tomy

Answers

This prospective investigation demonstrates that significantly reduced levels of VWF:Ag, VWF:CBA, and FVIII:C are linked to severe short-term hypothyroidism. Exogenous TSH administration has no impact on the coagulation parameters. According to these results, thyroid hormone insufficiency is probably the key factor contributing to coagulation changes in hypothyroid patients.

What is Thyroid hormone ?

Triiodothyronine and thyroxine are the two hormones known as thyroid hormones that the thyroid gland produces and secretes. They are tyrosine-based hormones whose main function is to control metabolism. Iodine makes up a portion of the molecules T3 and T4.

Iodine shortage may be the cause of thyroid issues. Inflammation can result from autoimmune illnesses when the thyroid is attacked by the immune system, causing either hyperthyroidism (caused by Graves' disease) or hypothyroidism (induced by Hashimoto's disease) (which may or may not cause pain),

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Read the paragraph from the section "Shellfish."

Lower pH values occur naturally on the West Coast during upwelling events, but recent observations indicate that CO2 originating from human activities is contributing to seasonal aragonite undersaturation. Scientists suspect that low pH may be a factor in the oysters' reproductive failure. More research is needed to disentangle potential acidification effects from other risk factors. Nonetheless, acidification is a potential factor in the current crisis to the multi-million-dollar oyster industry. The potential role of ocean acidification is encouraging new collaborations and accelerated research on ocean acidification and its biological impacts.

Which of the following can be inferred from the selection above?

A
Human activities are the primary cause of the aragonite undersaturation during upwelling events.
B
While some marine organisms are harmed by ocean acidification, others are helped by the lower pH levels in the ocean.
C
Collaborators are more motivated to study ocean acidification because of the economical impact it has on the oyster industry.
D
Ocean acidification is not to blame for the oysters' reproductive failure because lower pH values are natural during upwelling events.

Answers

Human activities are the primary cause of aragonite undersaturation during upwelling events.

What is an oyster?

Oysters are bivalve mollusks that obtain their food by filtering seawater for microscopic algae (phytoplankton), as well as some organic debris.

Marine life is getting affected because of the Increase in carbon levels and global warming. An increase in carbon level increases the solubility of water.

The oxygen level in the marine water decrease and the carbon dioxide level increases. The increase in solubility of carbon dioxide in water leads to a decrease in water pH level.

Therefore, Human activities are the primary cause of aragonite undersaturation during upwelling events.

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The division of human cells consists of a series of events, collectively called ________, or nuclear division, and ________, or division of the cytoplasm.

Answers

mitosis is the first one, cytokinesis is the second one

What will be the effect on protein function if each polypeptide adopted only a single, inflexible shape based on its primary structure.

Answers

If each polypeptide adopted only a single, inflexible shape based on its primary structure, the proteins' ability to regulate activity will be impaired.

In such a case, a protein will either be completely active or inactive, based on how they are folded.

Proteins are complex molecules composed of long chains of amino acids.

While protein folding refers to how these linear chains of amino acids are folded to render a biologically active protein.

If there is any abnormality in the folding, there will be no interaction with corresponding molecular partners and the protein will remain inactive which can harm various functions of the body.

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What is the function of carbohydrates?
A. To store energy
B. To help animals stay warm
C. To absorb the sun's energy
D. To store hereditary information

Answers

Answer:A

Explanation:

Why aren't viruses alive?

Answers

Viruses are not made out of cells, they can't keep themselves in a stable state, they don't grow, and they can't make their own energy. Even though they definitely replicate and adapt to their environment, viruses are more like androids than real living organisms.

A student adds 10 drops of a copper sulfate and sodium hydroxide solution to a test tube containing chicken broth. The solution undergoes a color change from blue to purple.

The presence of which organic molecule is indicated by the color change of the solution?


glycogen

protein

nucleosome

fatty acids and glycerol

Answers

The molecule whose presence is indicated is protein.

What is the food test?

The food test refers to the chemical methods that we could use to obtain the kind of food substance that we have in a sample. Let us recall that food is a chemical substance hence it is capable of chemical interaction with other chemicals.

One of the kind of food tests is the tests for proteins in which copper sulfate and sodium hydroxide solution is used. In this test, the color of the solution turns from blue to purple.

Hence the molecule whose presence is indicated is protein.

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if a parent with the genotype aa bb mates with a parent who is aa bb, what is the probability of an aa bb offspring?

Answers

When a parent with the genotype aabb mates with a parent who is aabb, the probability of an aabb offspring will be 100 % because it is a homozygous recessive condition.

The genotype refers to the genetic constitution of an organism. It provides knowledge about the alleles of the gene involved. It also tells if the trait is homozygous or heterozygous, dominant or recessive.

Homozygous recessive refers to the genotype where both the alleles of a gene are of similar type. Being recessive means that these alleles are only expressed when they are together in a homozygous state. With a dominant allele, the effect of recessive allele is completely masked.

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arrange the process of hemostasis in sequence. (separate letters by a comma and space [ex. a, b, c,…])

Answers

The sequence for the process of hemostasis is A, F, B, C, D, E.

What is Hemostasis?

Your body's natural response to an injury, hemostasis, stops the bleeding and repairs the damage. This skill typically works to your advantage by preserving blood and avoiding infections. The process can occasionally malfunction, leading to issues with excessive or insufficient clotting. There are four distinct steps to the hemostasis mechanism.

1) Blood vessel constriction.

2) The development of a transient "platelet plug."

3) The coagulation cascade is activated.

4) The last clot, or "fibrin plug," forms.

A series of enzymatic activations that result in the development of a clot containing platelets and fibrin polymer are made easier by hemostasis. While the process of tissue regeneration is taking place, this clot plugs the wounded area, manages the bleeding, and stops further bleeding.

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I understand that the question you are looking for is "Arrange the process of hemostasis in sequence. (Separate letters by a comma and space as follows: A, B, C, D)

A. Kidneys release erythropoietic factor

B. Increase in red blood cell production

C. Enzyme stimulates red bone marrow

D. Oxygen delivery increased to the tissues

E. Oxygen delivery decreased to the tissues

F. Decrease in red blood cell production"

the is the thin layer of the mucosa responsible for pulling the mucosa into its many folds which increases the surface area of the alimentary canal.

Answers

yes, Muscularis  mucosa - The stomach and small intestine's mucosa are pulled into undulating folds by a thin layer of smooth muscle that is constantly tensed. The surface area that is available for digestion and absorption is significantly increased by these folds.

The submucosa is located directly beneath the mucosa, as its name suggests. It joins the underlying muscularis to the overlaying mucosa by way of a large layer of dense connective tissue. It has blood and lymphatic vessels (which carry nutrients that have been absorbed), as well as a few submucosal glands that secrete digestive juices. Additionally, it functions as a passageway for the submucosal plexus, a densely branched network of nerves.

These layers compress to encourage mechanical digestion, expose more of the food to the chemicals that aid in digestion, and transport the food along the canal.

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match it in the correct order

Answers

1) sound waves reach the deers ears
2)the nerves in the ear send a signal to the brain
3)the brain processes the sound
4)the brain sends a message to the muscles
5)the deer runs away

masso, m., accurate and efficient structure-based computational mutagenesis for modeling fluorescence levels of aequorea victoria green fluorescent protein mutants. protein eng des sel 2020, 33.

Answers

Accurate and efficient structure-based computational mutagenesis for modeling fluorescence levels of aequorea victoria green fluorescent protein mutants is a research paper by Masso M.

What is the abstract?

Recently, experimental researchers determined the functional impacts (fluorescence levels) of over 46,000 single and multiple amino acid variations of the Aequorea victoria green fluorescent protein (GFP), and to characterize these effects, computational mutagenesis was applied. For each GFP mutant, the method produced a single score that reflected the overall shift in sequence-structure compatibility in comparison to native GFP as well as a vector of environmental perturbation (EP) scores that described the effects at each GFP residue location. By contrasting the sequence-structure compatibility scores with the functional data, a significant (P 0.0001) link between GFP structure and function was shown. Then, using random forest (RF) classification and tree regression machine learning methods, generated vectors for GFP mutants were utilized to construct predictive models of fluorescence.

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how do you distinguish between the bonds that compose the hydrophobic hydrocarbon tail of a lipid molecule versus the forces that drivelipid droplet formation (the hydrophobic effect)?

Answers

The difference between the bonds that compose the hydrophobic hydrocarbon tail of a lipid molecule versus the forces that drive lipid droplet formation (the hydrophobic effect) is hydrophobic hydrogen tail of a lipid molecule is the non water loving lipid whereas hydrophobic is the effect which is known as non water loving effect.

What is hydrophilic meant?

If a molecule is the “water-loving”, it is known as the ‘hydrophile’ (noun) that possesses a hydrophilic nature. In the contrast, if a molecule doesn’t like water (h2o) i.e. repel the water, it is known as the ‘hydrophobic‘. The terms hydrophilic and the hydrophobic are used to describe the molecules or  the substances based on how they react to the water molecules. The degree or the extent to which a molecule or a surface attracts water is known as the ‘hydrophilicity‘ of that molecule. Some of most common examples of the hydrophilic substances are sugar, salt, starch, and cellulose.

The tail of the phospholipid is the hydrophobic because it is composed of carbon and hydrogen atoms. If a molecule is made up of mostly of carbon and hydrogen atoms, it is a nonpolar or hydrophobic molecule. Carbon and hydrogen have the similar electronegativities, so they share the electrons equally resulting in the nonpolar bond. Because the tail of the phospholipid is the nonpolar, it does not interact with the water, whereas, Hydrophobic effect is just a tendency of non-polar molecules to come together so that they can avoid the water from their surface area as much as they can.

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Experiment: Robert wants to test different paper towels to see which

one absorbs the most liquid. He tries Bounty, Viva, and generic. He

fills a beaker with 100 mL of water and places once sheet of each

paper towel in the beaker. He then removes the paper towel and

calculates how much water it absorbed.


Question 1

What is the independent variable?

A. Amount of water absorbed

B. Brand of paper towel

C. Viva

D. The beaker


Question 2

What is the dependent variable?

A. Amount of water absorbed

B. Brand of paper towel

C. Bounty

D. The beaker


Question 3

What is a possible constant?

A. Amount of water absorbed

B. Brand of paper towel

C. Viva

D. Amount of time per trial


Question 4

What is the control group?

A. Amount of water absorbed

B. Brand of paper towel

C. Viva

D. This experiment did not have one

Answers

Answer:

Question 1:A

Question 2:B

Question 3:A

Question 4:D

Spontaneous movement of molecules and ions from an area of high concentration to an area of low concentration.

Answers

Spontaneous movement of molecules and ions from an area of high concentration to an area of low concentration is diffusion.

It is due to the concentration gradient that develops between two areas, that molecules move into or out of an area.

In the field of science, diffusion can be described as a process in which molecules tend to move from a region that has a higher concentration of molecules to an area that has a lower concentration of molecules. Such a process occurs along the concentration gradient and hence does not require energy.

The process of diffusion is utterly important in everyday life activities such as the exchange of gases between blood and alveoli occurs due to diffusion. A tea bag immersed in water is able to spread its colour due to diffusion.

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Choose the answer that lists the parts of the human circulatory system in order from highest to lowest degree of internal organization.

Group of answer choices

B-A-D-C

D-A-B-C

C-D-A-B

Answers

I think it’s D-a-b-c

microorganisms play key roles in the cycling of important nutrients in plant nutrition, particularly those of microorganisms play key roles in the cycling of important nutrients in plant nutrition, particularly those of carbon. nitrogen. carbon and nitrogen sulfur. carbon, nitrogen, sulfur, and phosphorus.

Answers

Microorganisms play key roles in the cycling of important nutrients in plant nutrition, particularly those of microorganisms play key roles in the cycling of important nutrients in plant nutrition, particularly those of carbon, nitrogen and sulfur.

What is Microorganisms?

Microorganisms, often known as microbes, are minute organisms that can be single cells or colonies of cells.

Ancient texts like the Jain scriptures from India's sixth century BC raised the specter of the potential existence of invisible microscopic life. In the 1670s, Anton van Leeuwenhoek used a microscope to observe microorganisms, which marked the beginning of the scientific study of microbes. Louis Pasteur disproved the hypothesis of spontaneous generation in the 1850s by discovering that bacteria were to blame for food degradation. Robert Koch determined in the 1880s that bacteria were to blame for tuberculosis, cholera, diphtheria, and anthrax.

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question 6 (true/false worth 2 points) (04.03 lc) during cellular respiration, chemical energy is converted to cellular energy. true false

Answers

It is true that during cellular respiration, chemical energy is converted to cellular energy.

What is cellular respiration?

Cellular respiration is a series of metabolic reactions that convert chemical potential energy stored in organic matter (such as glucose) into a form (cellular energy, which is ATP, means adenosine triphosphate) that can be directly used by the cell for a variety of activities.

It is also a process of oxidizing glucose to produce a large amount of energy, as well as carbon dioxide and water.

Thus, it can be concluded that the given statement is true.

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