Hitchhiker's thumb is inherited via two recessive alleles and causes a hyperextensibility of the thumb. The dominant allele causes a straight thumb phenotype. Predict the phenotypic and genotypic ratios from the following cross.

One parent with Hitchhiker's thumb crossed with a Straight thumbed individual who had a parent with Hitchhiker's thumb.

a. Phenotypic and Genotypic 1:1
b. Phenotypic 2:1 and Genotypic 1:1
c. Phenotypic 1:1 and Genotypic 2:1
d. Phenotypic and Genotypic 3:1

Answers

Answer 1

Answer:

a. Phenotypic and Genotypic 1:1

Explanation:

Two recessive alleles are required in order to be phenotypically affected for Hitchhiker's thumb. Hence, the genotype of the parent with Hitchhiker's thumb would be homozygous recessive.

Assuming the trait to be represented by the allele h, the genotype of the parent with Hitchhiker's thumb would be hh while the genotype of an individual with straight thumb who had a parent with Hitchhiker's thumb would be heterozygous, Hh.

Crossing the two individuals.

                        hh   x   Hh

Progeny:     Hh    hh    Hh    hh

Hh - Straight thumb

hh - Hitchhiker's thumb

Hence, the genotypic ratio is 1:1 while the phenotypic ratio is also 1:1.

The correct option is a.


Related Questions

Diffusion is a passive process that accounts for the movement of respiratory gases across the capillary membranes of alveoli.
True
False​

Answers

Answer:

True

Explanation:

Diffusion is a passive process (no energy required) in which the substance such as liquid and gases moves from an area of high concentration to an area of low concentration.

During respiration, carbon dioxide diffuses from the blood into the alveoli and oxygen diffuses from alveoli to blood across the respiratory membrane. The partial pressure of oxygen is low in the blood of the pulmonary capillaries and high in the alveoli. so diffusion allow movement of oxygen across the respiratory membrane from the alveoli into the blood.

Hence, the given statement is true.


Nucleic acids and carbohydrates are both types of what?
A. Macromolecules
B. Proteins
C. Elements
D. Atoms
SUBM

Answers

The answer is A. macromolecules

There are 4 types of macromolecules; lipids, proteins, carbs and nucleic acids

*Penguins are adapted to live in the antarctic. Which of the following is
NOT true?

A)The dark coloured feathers reflect heat from the sun
B)Their webbed feet make them powerful swimmers
C)They have overlapping feathers to waterproof them
D)They have thick skin and lots of fat to keep them warm

Answers

Answer:

B their webbed feet make them powerful swimmers

A student is given a list of traits and is asked to organize them in a Venn diagram as shown below.
Inherited Both Acquired
Traits
Wolf's social status
Tiger's stripes
Blood type A
A scar
Skin color
Musical talent
-
III
Q
Which traits should the student put in section II (Both)?
O a scar and blood type
tiger's stripes and wolf's social status
musical talent and wolf's social status
musical talent and skin color

Answers

Answer: a scar and wolf's social status

Explanation:

The acquired traits can be defined as the traits, which are only influenced by the environment of the organism. The acquired trait cannot be passed down to the offspring, as they are not genetically determined. A scar and the social status of any organism is dependent on the behavior of the organism to the environment, no genes code for both of these characters. So, scars and Wolf's social status is an acquired trait.

The trait that should be put in section II (Both) is "a scar", as scars can be acquired due to injury or trauma, but some people may also have a genetic predisposition to scarring.

What are inherited and acquired trait?

Inherited traits are characteristics that are determined by an individual's genetic makeup and are passed down from parents to their offspring through the process of reproduction. Examples of inherited traits include eye color, hair color, blood type, and facial features.

Acquired traits are characteristics that are developed during an individual's lifetime as a result of their interactions with the environment. Examples of acquired traits include scars, calluses, tanned skin, learned behaviors, and language proficiency.

While some traits may be either entirely inherited or acquired, many traits are influenced by both genetic and environmental factors. The complex interplay between nature and nurture contributes to the vast diversity of traits and characteristics found within the human population.

Learn more about traits, here:

https://brainly.com/question/29296703

#SPJ7

the force that drives fluxes of uncharged particles is :

a. heat
b. the chemical potential (μ)
c. dμ / dx
d. dμ / dt

Answers

Answer:

c. dμ / dx

I'm not sure but this all I can give you

Based on the objective you should feel comfortable calculating expected genotype frequencies when given observed allele frequencies. You should also be able to compare expected genotype frequencies from HWE to observed frequencies and determine if evolution is occurring. Here's a sample problem. You can do this without a calculator! Let's take the noob gene, a gene with two known alleles that determines feather color in the eastern lark. The two alleles, let's call them delta and gamma, can be sequenced. In fact, looking at a population in southern GA, you discover that 60% of the alleles in the population are the delta allele. So question 1, what is the percentage of the gamma allele in the population

Answers

Answer:

40% is the percentage of the gamma allele in the population.

Explanation:

Available data:

Two alleles, delta and gamma60% of the alleles in the southern GA population are the delta allele

What is the percentage of the gamma allele in the population?

According to Hardy-Weinberg, the allelic frequencies in a locus are represented as p and q, referring to the allelic dominant or recessive forms. The genotypic frequencies after one generation are p² (Homozygous dominant), 2pq (Heterozygous), (Homozygous recessive). Populations in H-W equilibrium will get the same allelic frequencies generation after generation. The sum of these allelic frequencies equals 1, this is p + q = 1.

In the same way, the sum of genotypic frequencies equals 1, this is

p² + 2pq + q² = 1

Being

p the dominant allelic frequency, q the recessive allelic frequency, p² the homozygous dominant genotypic frequency q² the homozygous recessive genotypic frequency 2pq the heterozygous genotypic frequency

If the percentage of delta allele in a population is 60%, this means that its frequency is 0.6. By clearing the equation p + q = 1, we can calculate the gamma allele frequency. This is:

p + q = 1

0.6 + q = 1

q = 1 - 0.6

q = 0.4

Then the percentage of gamma allele in the population is 40%.

We can also think about it like this:

If the sum of the allelic frequencies equals 1, then 1 is 100% of the allelic frequencies. And if the percentage of delta allele in a population is 60%, then 40% is the percentage of gamma allele.

13. Ranchers lobbied the government to eradicate wolves from Yellowstone National Park. Five years later the deer population had increased fivefold. The following winter 70% of the deer starved to death. Explain why this was bound to happen.

Answers

Answer: The overgrowth in deer population led to a food shortage.

Explanation:

Since the eradication of the wolves, the deer had no predator to keep their total population in check. Due to the vast amount of deer the food in the area was being eaten at a faster rate. Most of the deer died do to their environment not being capable of feeding that many deer.

(I hope this helps! I tried my best.)

Select the correct answer.
Which type of energy is thermal energy a form of?
A.
chemical energy
B.
kinetic energy
C.
magnetic energy
D.
potential energy

Answers

Answer:

right answer is

B

Kinetic energy

The answer is B kinetic energy

Complete each sentence by dragging the proper word or phrase into the appropriate position. Then place each sentence in order from the largest to the smallest cavity size being described
Drag the text blocks below into their correct order.
1. The________ are found deep in the diaphyses of long medullary cavities bones and are filled with yellow marrow in the adult.
2. Osteocytes maintain contact with neighboring osteocytes in adjacent lamellae via dendrite-like extensions through __________
3. Filled with matrix, , which are osteoblasts encased in perforating canals are found between layers of concentric lamellae nutrient foramen
4. Located in the middle of osteons, the contain the osteocytes blood vessels, and nervous supply of the compact bones. osteons
lacunae
central canals
canaliculi

Answers

Answer:

The medullary cavities are found deep in the diaphyses of long medullary cavities bones and are filled with yellow marrow in the adult.

Osteocytes maintain contact with neighboring osteocytes in adjacent lamellae via dendrite-like extensions through canaliculi.

Filled with osteocytes, which are osteoblasts encased in matrix, lacunae are found between layers of concentric lamellae.

Located in the middle of osteons, the central canal contain the blood vessels, and nervous supply of the compact bones

Explanation:

- The medullary cavities are central cavities in the bones. In adults, these cavities are filled with yellow marrow  (adipose tissue).

- The canaliculi are small protoplasmic projections between the lacunae of ossified bones.

- The astrocytes are the most common type of bone cell.

- The lacunae are spaces where osteocytes are located in the mature bones

-  The central canal provides nourishment to the osteocytes which collectively form the osteon.

1. Summarize the six ways the loss of Arctic ice is affecting everyone.

six ways are temperature,coastal communities,food,shipping,wildlife,permafrost

Answers

Answer:

Explanation:

Artic Ice are melting due to change in the climatic system as a result of global warming. The active increase in human activity resulting in global warming will continually perpetuate the decrease in artic Ice.

Artic heat help to balance temperature or heat on the earth surface by reflecting heat back into the environment. When the artic Ice is reduced, the amount of heat reflected is also reduces.

Coastal community - a continuous rise in ocean level can lead to flooding which will affect the coastal community surrounding the ocean. An the ocean has been incredible gradually over the pass decades.

Food - Reduction in the artic Ice car Lea to increase heat affect crop growth through damage by heat stresses leading to an increase price rate of food.

Meltng of Ice increase the shipping routes causing more harm through ship wrek.

Melting of Ice can leave to loss of animals that depends on it for survival.

Permafrost occurs when the ground is permanently block or frozen leading to accumulation of methane gases that causes global warming.

_________10. Which of the following groups of plants carry out light dependent and light independent reactions of
photosynthesis in separate cells?
A. Plants with chlorophyll C. C3 – plants
B. CAM Plants D. C4 – plants

Answers

Answer:

Plants with chlorophyll

Which of the following is false?
A. When a maternal effect gene is seen, the offspring will demonstrate the phenotype of the mother's genotype.
B. In maternal effect, an offspring will have the genotype of their mother.
C. In a reciprocal cross, if an offspring has the mother's phenotype for both crosses, cytoplasmic inheritance is responsible.
D. The direction of shell coiling in Lymnaea peregra is influenced by the orientation of the first cleavage division.
E. It is safe to say that a maternal effect is caused by the genotype, not the phenotype, of the parent producing the egg.

Answers

Answer:

Answer is D.

Explanation:

The first cleavage division can be explained or described as the series of first cellular division of the zygote after fertilization.

In this case, the process of recoiling of the shell of the snail can not be categorized as one of the examples at this stage.

There are _______ different amino acids used to make proteins, and different condones code for different amino acids.

Answers

Answer: there are only 20 different amino acids but 64 possible codons

Explanation:

A scientist is tracking object orbiting the sun that is found between Mars and Jupiter which additional feature can be used to determine the object is an astroid

Answers

Answer:

The options are not given. Here are the options;

produces a coma

has an irregular shape

has a tail of ice and dust

produces a streak of light.

The answer is has an irregular shape.

Explanation:

Asteroid are small objects that are too small to be called planets that revolve round the sun. They are smaller in size. The mass of the asteroids is less than the size of the Earth's moon.

Asteroids are leftovers from the formation of our solar system about 4.6 billion years ago. Earlier, the formation of Jupiter prevented any planetary bodies from forming in the gap between Mars and Jupiter, which make the small objects that were present to collide with each other and fragment into the asteroids.

Asteriods produce irregular shape.

Answer:

the answer is has an irregular shape or b

Explanation:

NASA’s Kepler mission found evidence of several potentially habitable exoplanets, raising the possibility that life may have evolved independently outside of our solar system. If NASA found a novel lifeform, we would expect it to use energy molecules based on similar principles as lifeforms on Earth. The organism would likely use molecules with _____________ bonds. It might use two separate molecules, one serving as a rapidly utilizable energy currency and another molecule serving as long-term energy storage.
a. high energy.
b. low energy.
c. hydrogen.
d. electrostatic

Answers

Answer:

c. hydrogen.

Explanation:

Earth is full of different substances. Hydrogen bonding is  a partial inter molecular bonding between a lone pair and an electron rich donor. Some of the most important molecules here on earth are held by hydrogen bonding.

Hydrogen bonding is useful in inorganic and organic molecular combination.

Which fossil fuel should be available for the longest time if current usage continues?

Answers

Coal
Coal and natural gas are expected to last a little longer. If we continue to use these fossil fuels at the current rate without finding additional reserves, it is expected that coal and natural gas will last until 2060. However, the consumption of natural gas grew considerably last year, rising by 4.6%.

Predict which one of the following organisms will have the highest percentage of unsaturated fatty acid chains in their membranes: Group of answer choices thermophilic bacteria desert iguana humans antarctic fish

Answers

Answer:

Humans

Explanation:

Humans are bigger than most beings and some people are extremely obese.

The organisms that have the highest percentage of unsaturated fatty acid chains in their membranes are ANTARCTIC FISH.

Unsaturated fatty acid chains have one or more double bonds, while saturated fatty acid chains do not contain any double bonds.

When the temperature decreases, the composition of the phospholipids bilayer membrane becomes more unsaturated to be able to maintain different properties such as homeoviscosity.

In consequence, membrane lipids exhibit the highest percentage of unsaturated fatty acid chains during cold acclimation.

In conclusion, the organisms that have the highest percentage of unsaturated fatty acid chains in their membranes are ANTARCTIC FISH.

Learn more in:

https://brainly.com/question/3007736

A study from the National Institutes of Health states that the human body contains trillions of microorganisms that make up 1% to 3% of the body's mass. Use this information to estimate the average mass of a microorganism.

Answers

Answer:

If the mass of the human body is 60 kg so the average mass of microorganism is 1.2 kg.

Explanation:

If we suppose the mass of human body is 60 kg and we know the percentage that is 1 to 3% so we will take the average microorganism mass of which is 2%. So by doing multiplication of 60 with 2 and then divided by 100, we get 1.2 kg. The reason for dividing by 100 is that the average mass present in percentage form so for converting the percentage into standard form we have to divide it by 100. So we conclude that in every human with a mass of 60 kg have 1.2 kg microbes present in their body.

you have selected the following prediction to test: Previously thinned forests will have higher tree survival than adjacent forests that were not thinned. Now you need to define the key variables that you will use to test this prediction. For the following variables, sort them as independent variables, dependent variables, or variables that should be controlled (held constant)1. thinning or no thinning before the fire elevation of the site 2. dominant tree species 3. tree survival rate after the fire A. Independent variableB. Dependent variable C. Controlled variable

Answers

Answer:

A. Independent variable 2. dominant tree species

B. Dependent variable  3. tree survival rate after the fire

C. Controlled variable 1. thinning or no thinning before the fire elevation of the site

Explanation:  

A. An independent variable doesn't undergo changes during the experiment because it is not conditioned by other variables in the experiment. In this example, dominant tree species represent a variable that is independent of the experiment itself.

B. A dependent variable is those that you need to measure and depends on the other factors in the experiment. In this example, tree survival is dependent on the factors that affect the results (i.e. humidity in the trees, presence of resinous material in the trees that are non-combustible, etc.)

C. A controlled variable is those that we use to observe an expected outcome in the experiment and therefore it is used to compare with the test group. In this case, thinning or no thinning are used as positive and negative controls, respectively, because they enable their comparison with the test group in the experiment.  

hello there.
Explain that different sequences of amino acids give different shapes to protein molecules

Answers

Explanation:

The sequence of amino acids in the chain determines how the chain will fold up to make the protein, so different proteins have different three-dimensional shapes. ... This is because proteins form attachments and interact with many other molecules and structures inside organisms.

Given two types of starfish, gold ones and purple ones, that are members of the same species. In your sample area, there are 325 gold starfish and 150 purple starfish (assume purple is dominant)

A. Find the genotype frequencies for "SS", "Ss", & "ss"
B. Find the allele frequencies for "S" (p) & "s" (q)

Answers

Answer: I believe I can fly

Explanation:

I believe I can touch the sky.

JK Love you bae

What are the characteristics of erythrocytes? Erythrocytes contain a nucleus, mitochondria, and ribosomes. Erythrocytes synthesize proteins. Erythrocytes can change shape to squeeze through microcirculation. Erythrocyte proliferation is stimulated by erythrocyte colony-stimulating factor (E-CSF).

Answers

Answer:

Erythrocytes can change shape to squeeze through microcirculation.

Explanation:

Deformability is the ability of the red blood cells to change shape so as to enable them squeeze through tight or small spaces including capillaries.

Ill mark you as Brainliest and give you points !!!!!

Answers

The first one is B and the second one is B , brainliest would appreciated

Answer:

The independent variable is:

the factor that is changed in an experimentthe change does not depend on other factors

The dependent variable is:

what is going to be affectedwhat is being testedwhat is being observed or measured

10. What happens to DNA strands during hybridization?
O It binds together.
O It splits from each other.
ma
O It is degraded.
O It is sliced into different sections.

Answers

Answer:

it binds together

Explanation:

dna is commonly present in the shape of a molecule with double strands. In a similar way, these two molecules connect to each other in a mechanism called hybridisation. DNA naturally, the new strand hybridizes to the old strand when it is replicated.

hope this helped!

During hybridization, DNA strands bind together. The correct option is A.

The process of joining two complementary strands of DNA from various sources to create a double-stranded molecule is referred to as hybridization.

The complementary DNA strands join together during this phase and create strong hydrogen bonds between their corresponding base pairs. Adenine (A) and thymine (T) and guanine (G) and cytosine (C) couple up specifically to form this interaction.

Numerous molecular biology procedures, including DNA hybridization tests, polymerase chain reaction (PCR), and DNA sequencing, frequently employ hybridization.

Hybridization enables the identification and amplification of particular DNA sequences as well as the analysis of genetic data by allowing the complimentary strands to come together.

Thus, the correct option is A.

For more details regarding Hybridization, visit:

https://brainly.com/question/32752412

#SPJ6

Your question seems incomplete, the probable complete question is:

10. What happens to DNA strands during hybridization?

A. It binds together.

B. It splits from each other.

C.  It is degraded.

D. It is sliced into different sections.

If you have a concern about fluoride in your drinking water, how do you get more information?

Answers

Answer:

Contact the Centers for Disease Control and Prevention (CDC).

Explanation:

What cell type are involved in the secretion thyroglobulin ?

Answers

by thyroid epithelial cells and secreted into the lumen of the follicle - colloid is essentially a pool of thyroglobulin.

By thyroid epithelial cells and secreted into the lumen of the follicle - colloid is essentially a pool of thyroglobulin.

What is Thyroglobulin?

The amount of thyroglobulin in a sample of your blood is measured by a thyroglobulin test. Your thyroid produces a protein called thyroglobulin. A little gland in your neck with a butterfly form is your thyroid.

It produces hormones that regulate a variety of bodily functions, such as your heart rate and how quickly you burn off calories from food.

One kind of test for tumor markers is the thyroglobulin test. In reaction to cancer in your body, cancer cells and/or normal cells produce molecules known as tumor markers. Small levels of thyroglobulin are typically released into your bloodstream by your thyroid.

Therefore, By thyroid epithelial cells and secreted into the lumen of the follicle - colloid is essentially a pool of thyroglobulin.

To learn more about thyroglobulin, refer to the link:

https://brainly.com/question/14619705

#SPJ2

Are zoos beneficial to animals

Note:This is a Debate​

Answers

Answer:

I think they are not beneficial to animals

Explanation:

because

1.they are not free to live for themselves , find mates and have children

2.they are there so as the people can get money

Answer:

Proposition:

Zoos are beneficial  for animals because :

- Keeps them away from poachers

- Medical care is provided

- protects them from predators

Opposition:

- in captivation most animals get depressed

- for doing tricks they are left starving

- they are kidnapped from the jungles away from the parents

(THE POINTS DEPEND ON THE TYPE OF DEBATE (THW;THBT;THR;THS))

(I have given it in general)

HOPE IT HELPS :)

PLEASE MARK IT THE BRAINLIEST!

what is evaporation​

Answers

the process of turning from liquid into vapor.

Answer:

Evaporation is the process of turning liquid to vapor form.

Which would be a result of a malfunctioning excretory system?
paralysis
memory loss
toxic buildup
difficulty breathing

Answers

Toxic buildup
The excretory system has to do deal with excreting dangerous and harmful materials from our body

Answer:

toxic buildup.

Explanation:

The excretory system has to do with excreting perilous, harmful materials from the body. If it malfunctions, these materials stay in the body. Therefore, the result of a malfunctioning excretory system would be toxic buildup.

Which statement is true of viruses? A. Viruses do not consist of cells, but they have cell membranes, cytoplasm, ribosomes, and other cell organelles. B. Viruses do not consist of cells; they lack cell membranes, but do have cytoplasm, ribosomes, and other cell organelles. C. Viruses do not consist of cells; they also lack cell membranes, cytoplasm, ribosomes, and other cell organelles. D. Viruses are cells with cell membranes, cytoplasm, ribosomes, and other cell organelles.

Answers

Answer:

C. Viruses do not consist of cells; they also lack cell membranes, cytoplasm, ribosomes, and other cell organelles.

Explanation:

Viruses are only composed of a couple things: strands of nucleic acid that can be DNA or RNA, a protein coat called a capsid, and potentially a glycolipid coat to protect the outside.

There are no organelles, nor are there cells. Keep in mind that a virus is nonliving, so D is utterly wrong.

Other Questions
just the red triangle use the Phytogram theorem please :( Can someone please write a short summary of the Cold War policy of containment? What could happen to a persons body as a result of unhealthy eating and a sedentary lifestyle? The digestive system would safely regulate blood sugar levels. A balance of energy would occur due to equal caloric input and output. A buildup of cholesterol plaque would begin in the bloodstream.Cells would be able to perform normal cell function and maintenance. Management of Carla Vista, Inc., is planning to raise $1,215,000 in new equity through a private placement. If the sale price is $20.25 per share, how many shares does the company have to issue A tank contains 5,000 L of brine with 13 kg of dissolved salt. Pure water enters the tank at a rate of 50 L/min. The solution is kept thoroughly mixed and drains from the tank at the same rate.Required:a. How much salt is in the tank after t minutes? b. How much salt is in the tank after 20 minutes? Evaluate x y for x = 3 and y = 12. Your answer: A. 0.25 B. 4 C. 9 D. 36 The separation of powers within the federal government ensures that decisions made are in the best interest of the country the executive branch will remain the most powerful branch of government the states will be able to function independently of one another foreign countries will not be able to interfere with our government Which story premise is the best example of magical realism?O A. At the battle of the bands, the Lizards face off against UraniumNightmare.O B. Bo discovers the lost city of Atlantis but can't find a gas stationanywhere.O C. A wizard plunders an ancient dungeon for the secret of how totame dragons.D. Aliens from outer space invade Earth, and only Capybara Man canstop them. Find the produce 2 1/3 times 3 1/2 4. A neutrally charged conductor has a negatively charged rod brought close to it, and thus has an induced positive charge on the surface closest to the rod. What can we say about the overall charge on the conductor Please answer this correctly g B. PROTEINS 1. Name the gastric enzyme that initiates protein digestion. Explain how this enzyme is activated. Pepsin is the gastric enzyme that initiates protein digestion. It is activated by stomach acid into the active form. It then breaks down the protein in our food into smaller particles like peptide fragments and amino acids. 2. Name the ducts in the pathway by which pancreatic juice flows from the pancreas to the duodenum. The Pancreatic duct. 3. Describe 3 ways the body uses these amino acids.. What is the money an investor receives above and beyond the money initially invested called? Find n so that (4/5)^3 (4/5)^-6 = (4/5)^2n-1 Please answer this correctly How would you use a completely randomized experiment in each of the following settings? Is a placebo being used or not? Be specific and give details. a. A charitable nonprofit organization wants to test two methods of fund-raising. From a list of 1000 past donors, half will be sent literature about the successful activities of the charity and asked to make another donation. The other 500 donors will be contacted by phone and asked to make another donation. The percentage of people from each group who make a new donation will be compared. b. A tooth-whitening gel is to be tested for effectiveness. A group of 85 adults have volunteered to participate in the study. Of these. 43 are to be given a gel that contains the tooth-whitening chemicals. The remaining 42 are to be given a similar-looking package of gel that does not contain the tooth-whitening chemicals. A standard method will be used to evaluate the whiteness of teeth for all participants. Then the results for the two groups will be compared. How could this experiment he designed to be double-blind? c. Consider the experiment described in part (a). Describe how you would use a randomized block experiment with blocks based on age. Use three blocks: donors younger than 30 years old. donors 30 to 59 years old. donors 60 and older. Answer 5, 6 , and 7 by today please. Jeremy jogged 75 yards from his house to school how many feet did Jeremy jog? Solve this problem any way you choose. After a volcanic eruption, lava flows on the surface of the Earth. After the lava has time to cool, scientists notice that plants are starting to grow on the lava surface. What kind of ecological process could you infer is happening and why? The woman marked with a question mark is your friend. Knowing that you are taking Genetics, she comes to ask you for advice: she wants to have children, but is afraid that they will be sick with the disease. Her husband and her mother have no family history of HD. What is the probability that she is sick? What is the probability that her children will be, without knowing her own status regarding the disease?