igf2bp3 enhances an aggressive tumor cell phenotype by impairing mirna-directed downregulation of oncogenic factors

Answers

Answer 1

Although the oncofetal IGF2 mRNA binding proteins (IGF2BPs) are increased in the majority of malignancies, little is known about the unique functions of their paralogues in tumour cells. IGF2BP1 exhibits significantly conserved carcinogenic potential in a panel of five cancer-derived cell lines.

What are Tumor cells ?

A mass of tissue that develops abnormally when cells do not die on schedule or expand and divide more often than they should. Cancer-free tumours might be benign or malignant (cancer). Although benign tumours can become enormous, they do not penetrate or spread to surrounding tissues or to other areas of the body.

Tumors, which are tissue masses, can develop from these cells. Tumors may or may not be malignant (benign). Cancerous tumours can move to distant parts of the body to produce new tumours, invade neighbouring tissues, or both (a process called metastasis). Malignant tumours are another name for cancerous tumours.

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Related Questions

The Co2 you breath out comes out of which process?

Answers

respiration :). hope that helped

Answer:

cell respiration

Explanation:

The carbon dioxide breathed out is a by-product of the process of cell respiration, as is water. In this process, energy is produced in the mitochondria of cells.

algor mortis is the gradual cooling of the body after death until it reaches the temperature of the air around it.

Answers

it is true that algor mortis is the gradual cooling of the body after death until it reaches the temperature of the air around it.

What is algor mortis?

The gradual cooling of the body after death until it reaches the temperature of the surrounding air is known as algor mortis.

For forensic autopsies, the cause of death is frequently self harm or homicide, rather than disease or other natural causes.

Fresh, early decomposition, advanced decomposition, skeletonization, and extreme decomposition are the five stages of decomposition.

The early decomposition phase is marked by skin slippage and hair loss.

Thus, the given statement is true.

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Describe the impact of cutting down OR burning large areas of forest on the recycling of Carbon

Answers

Answer:

When forests are cut down, a large portion of the stored carbon is released back into the atmosphere as CO2. Deforestation and forest degradation contribute to global warming in this way.

Explanation:

When forests are cut down, burned, or otherwise removed, they emit carbon rather than absorb it. Deforestation and forest degradation account for approximately 15% of total greenhouse gas emissions. These greenhouse gas emissions contribute to rising temperatures, shifting weather and water patterns, and an increase in the frequency of extreme weather events.Climate change can have an impact on forest creatures by altering their habitats and decreasing the availability of food and water. Some will be able to adapt by shifting to higher elevations or latitudes, but species loss is possible.

Why do concentration gradients exist?

A.To differentiate the organelles from the molecules.
B. To contrast between the high and low concentration of molecules.
C. For cells to reach exocytosis
D. For molecules to undergo facilitated diffusion.

Answers

B. To contrast between the high and low concentration of molecules.

for example a solution with a higher solute concentration than the inside of the cell is called hypertonic

What advantage does having a myelin sheath produced by Schwann cells have for the impulse?

Answers

Answer:

Spontaneous repair of peripheral nerves is made possible by Schwann cells, which surround the nerve fibers with an insulating layer, myelin. This fatty layer protects the nerves and increases the speed of transmission of nerve impulses.

Explanation:

Schwann cells are small elements that are created in order to form a layer around the axon of the nerves of the peripheral system. These cells surround the axon by an extensive layer of myelin that is discontinued by the presence of Ranvier's node. Myelin is a single cell organelle, a modified extension of the plasma membrane of the Schwann cell in the peripheral nerve. Its elaboration depends on the regulated expression of a set of genes in the myelinating glia, for which the Schwann cells require axonal contact, as well as to maintain the expression of these genes. Myelin acts as an electrical insulator that facilitates the conduction of the nerve impulse, it helps when the axons must regenerate, that is, when there is some injury or disease that prevents cell transmission. The goal is to help the nerve regenerate and grow again to reach the target tissues. Once the nerve is repaired, the cell regains its ability to produce myelin to cover the nerve with the insulating layer and allow the correct transmission of nerve impulses.

1.
All living things are composed of cells.
Which action is not accomplished by repeated cell
division?
A.
a plant developing new leaves
B.
a broken bone growing back together
C.
a plant using sunlight to make its own foods
food
D.
an eight-pound baby growing into a 100-pound
teenager

Answers

Answer:

C

Explanation:

Everything else has to do with growth but C is talking about food/energy.

A plant using sunlight to make its own foods is accomplished by repeated cell division.

What do you mean by cell division?

Cell division is the process by which a parent cell divides into two daughter cells. Cell division usually occurs as part of a larger cell cycle in which the cell grows and replicates its chromosome before dividing.

There are two types of cell division: mitosis and meiosis. Most of the time when people refer to “cell division,” they mean mitosis, the process of making new body cells. Meiosis is the type of cell division that creates egg and sperm cells. Mitosis is a fundamental process for life.

In eukaryotic cells, or cells with a nucleus, the stages of the cell cycle are divided into two major phases: interphase and the mitotic (M) phase.

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themeli, m. et al. generation of tumor-targeted human t lymphocytes from induced pluripotent stem cells for cancer therapy. nat. biotechnol.31, 928–933 (2013)

Answers

In adoptive T-cellular therapy for cancer and infectious diseases is hampered by way of the shortage of effectively to be had, antigen-particular, human T lymphocytes.

Pluripotent stem cells should provide an infinite source of T lymphocytes, but the therapeutic potential of human pluripotent stem cellular-derived lymphoid cells generated so far remains uncertain. right here we combine triggered pluripotent stem mobile and chimeric antigen receptor technologies to generate human T lymphocytes cells focused, an antigen expressed by means of malignant B cells, in tissue subculture.

T lymphocyte cells potently inhibit tumor increase in a xenograft model. This method of generating healing human T cells in the dish may be useful for cancer immunotherapy and other scientific packages.

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A man who is homzygous for Blood Type A has a child with a woman who is heterozygous for Blood Type B. What is the likelihood that their child will have Blood Type AB?
0%
25%
50%
75%​

Answers

Answer:

75%

Explanation:

What is a Example of Newton 1st Law and how does it show inertia

Answers

Answer:

Newton's first law is the law of inertia: An object in motion will remain in motion until acted upon by an outside force.

Example:

a wheelbarrow rolling down a hill does not stop rolling until it crashes into a tree.

Dna sequences in many human genes are very similar to the sequences of corresponding genes in chimpanzees. The most likely explanation for this result is that.

Answers

The most likely explanation for this result is that humans and chimpanzees share a relatively recent common ancestor.

Scientific research has shown that about 98.8% of the human genome matches with a chimpanzee genome. The occurrence of such similarities between genomes of two organisms predicts that both the organisms had a common ancestor in the near past.

The DNA studies of an organism help to determine how closely or distinctively related two species of organisms are. Organisms with a similar genome are considered to be having a common ancestor in the near past. As humans and chimpanzees have a vast similarity index between their genomes, this explains that both these organisms evolved from a common ancestor in the near past.

These evolutionary relationships help scientists to study how a particular organism evolved into the form that can be seen today.

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kreuz pc, steinwachs mr, erggelet c, et al. results after microfracture of full-thickness chondral defects in different compartments in the knee. osteoarthr cartil. 2006;14:1119–1125.

Answers

Microfracture is a minimally invasive procedure that effectively treats minor cartilage abnormalities in the near term. The ICRS-score is the most telling indicator of a decline in outcomes that begins 18 months following surgery. Young individuals with femoral condyle abnormalities had the highest prognostic odds.

How does microfracture work? 

Because of their great efficacy, low cost, and short operating times when compared to other surgical methods, microfractures are frequently used as the first surgical option for the treatment of osteochondral lesions. Despite the patellofemoral compartment being the second most prevalent compartment for such lesions, the results of microfractures for retropatellar chondral abnormalities are mediocre when compared to other compartments of the knee. The patella's mobility, which is particularly noticeable when the patient's knee is extended, as is the situation in this kind of surgery, is one of the main causes of the inferiority.

Manual pressure has historically been used to overcome this hurdle, but this method is unreliable and prone to technical issues like skiving of the awl and restricted operating perspective, as well as consequences like fractures. This Technical Note describes a novel internal stabilization technique we call "house-on-stilts" that involves several Kirschner wire fixations into the patella and femur to immobilize the patella. This method supports both the debridement step before microfracturing without adding to operating costs or time.

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animal cell example and major distinguishing characteristics​

Answers

Answer:

Animal cells have slight differences to the eukaryotic cells of plants and fungi. The clear differences are the lack of cell walls, chloroplasts and vacuoles and the presence of flagella, lysosomes and centrosomes in animal cells. Plant and fungal cells have cell walls

Which component is missing from the process of cellular respiration?



________ + Oxygen → Carbon Dioxide + Water + Energy

Answers

Answer:

The answer is glucose

Explanation:

Glucose + Oxygen -> Carbon dioxide +Water + Energy

if you think about it it is just photosynthesis backwards

Can you please help me

Answers

Answer:

i see this was posted 3 days ago, do you still need help with this question?

Explanation:

in the study described in the passage, the injection of adrenaline is acting in a manner most analagous to:

Answers

In the study described in the passage, the injection of adrenaline is acting in a manner most analagous to Unconditioned stimuli.

What is conditioned and unconditioned stimulus?Unconditioned stimulus are those for which the individual has not undergone conditioning; they cause a certain response to emerge organically. An unconditioned stimulus is one that elicits an intuitive response. In Pavlov's experiment, the meal functioned as the unconditioned stimulus. A reflexive response to a stimuli is referred to as an unconditioned response. In Pavlov's experiment, the dogs' unconditioned response was their salivation for food.Despite the fact that the individuals have not been trained to respond in such way, an adrenaline injection encourages a response. When combined with an unconditioned stimulus, a conditioned stimulus—which by definition does not ordinarily elicit a response—can gradually train people to react similarly.

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Which hormonal imbalance would the nurse suspect in a client who has low serum sodium levels? epinephrine glucagon calcitonin aldosterone

Answers

Aldoaterone hormonal imbalance would the nurse suspect in a client who has low serum sodium levels.

What is the most typical reason for low sodium levels?

So a renal issue is the most typical cause of low sodium. The body retains excess water when the kidneys aren't working properly, which can happen with chronic renal disease or even brief dehydration. Additionally, the sodium level in the body is lowered by the body's sodium to water ratio.

Adrenal gland insufficiency affects your adrenal glands ability to produce hormones that help maintain your body's balance of sodium , potassium and water.

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if you study the interactions between cheetahs and the thomson's gazelles they prey upon, you would primarily be doing ecology.

Answers

if you study the interactions between cheetahs and the thomson's gazelles they prey upon, you would primarily be doing ecology.

community

What is ecology?

A subfield of research called ecology includes the fields of human science, population, community, ecosystem, and biosphere. Ecology is the study of organisms, the environment, and the interactions between the organisms and their surroundings. Numerous levels, including organism, population, community, biosphere, and ecosystem are researched.

The main objective of an ecologist is to increase their understanding of the life processes, habitats, interactions, and biodiversity of species.

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How do sand particles compare to other types of soil particles? A. They are warmer. B. They are smaller. C. They are wetter. D. They are larger.​

Answers

Answer:

A

Explanation:

Translate the following AUG CCC AUU AUC CGG

Answers

Answer:

These are proteins right??

Explanation:

if they are it means

double helix (transcribed strand)

DNA double helix

RNA transcribed

appropriate RNA anticodon

amino acids incorporated

Answer:

Met Pro lle lle Arg or TAC GGG TAA TAG GCC

Explanation:

wasn't sure if you wanted me to translate these into amino acids or DNA.

i need help with csi wildelife bruh

Answers

Answer:

The region where the tusks were seized is roughly the same distance from three national parks: Garamba National Park, Bomu Wildlife Reserve, and Okapi Wildlife Reserve. Are these tusks from the elephants that were killed in Garamba National Park or did they come from one of the other parks?

You will use DNA analysis to see if the DNA extracted from the tusks found in the truck matches any of the DNA isolated from the dead Garamba Park elephants.

Explanation:

Help me pls! In your own words, explain how the information carried by mRNA is used in the ribosome to form proteins. Be sure to include the following words and phrases: nitrogenous base, amino acid, codon, polypeptide.

Answers

Answer:

the messenger RNA (mRNA) is decoded in a ribosome, outside the nucleus, to produce a specific amino acid chain, or polypeptide. The polypeptide later folds into an active protein and performs its functions in the cell

Explanation:

The information carried by mRNA is used in the ribosome to form proteins in the following way:

Messenger RNA is nothing more than a copy of the instructions contained in the gene, it is responsible for copying and carrying the exact sequence of amino acids (called a polypeptide) from DNA to the ribosomes.

In other words, the amino acid sequence of a protein comes from information stored in the base sequence of nucleic acids, specifically in the mRNA sequence.

This information written in a four-letter language, the nitrogenous bases (A, G, C, T), must be translated into a language that is based on 20 amino acids, known as the genetic code.

The sequence of bases of the messenger RNA is the one that determines the amino acid sequence, and the one used, therefore, for the description of the code.

The molecules in charge of transporting the amino acids to the ribosome and of recognizing the codons of the messenger RNA during the translation process are the transferring RNAs.

Therefore, we can conclude that mRNA carries the exact amino acid sequence of DNA to ribosomes, where instructions are followed and protein synthesis proceeds.

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2. Curly hair is recessive (s), and straight hair is dominant (S). A woman with curly hair (ss) marries a man who is a true breeder for straight hair (SS). What percentage of their children will have curly hair, and what percentage of them will have straight hair?





% Curly-

% Straight-

Answers

Curly 0%
Straight 100% or
Curly 25% and straight 75%
Curly -50
Straight-50

HELP ME PLEASE

All of the following are required for photosynthesis to occur EXCEPT:
A.) Sunlight
B.) carbon dioxide
C.) oxygen
D.) chloroplast ​

Answers

Answer:

C. Oxygen

Explanation:

Using Sunlight, Carbon, and Chloroplast plants turn all of that into carbohydrates and oxygen. That process is called photosynthesis. Were plants use to make themselves food.

Answer:

C, oxygen.

Explanation:

after photosynthesis finishes, the plant produces oxygen, thus, it is not required.

Many soil-dwelling bacteria produce molecules that can be naturally synthesized and kill other species of bacteria. What are these bacteria-killing molecules called?.

Answers

The correct answer is antibiotics. Antibiotics are the bacteria-killing molecules that Many soil-dwelling bacteria produce.

Antibiotics are potent medicines that fight certain infections and, when used correctly, can save lives. They either prevent bacteria from reproducing or kill them. White blood cells (WBCs) attack harmful bacteria, and even if symptoms appear, the immune system is usually able to cope with and fight off the infection. However, there are times when the number of harmful bacteria is excessive, and the immune system is unable to combat them all. Antibiotics come in handy in this situation. Penicillin was the first antibiotic. Penicillin-based antibiotics, such as ampicillin, amoxicillin, and penicillin G, are still available and have been used for a long time to treat a variety of infections.

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PLEASE HELP GUYS!!Scientists think an "RNA world" existed on Earth long before DNA evolved.
Why do scientists think that RNA is a likely candidate to have been the first
genetic material?
O A. Some RNA can catalyze reactions.
OB. RNA is less complex than DNA.
OC. The Miller-Urey experiment yielded RNA but no DNA.
OD. Fossilized organisms containing RNA predate those containing
DNA.

Answers

Answer:

(D)

Explanation:

RNA has great capability as a genetic molecule; it once had to carry on hereditary processes on its own. It now seems certain that RNA was the first molecule of heredity, so it evolved all the essential methods for storing and expressing genetic information before DNA came onto the scene.

Answer:

Its B

Explanation:

Which of the following statements is true?

A) Mitosis and meiosis have the same number of cellular divisions.
B) Mitosis is used for growth and repair of body cells.
C) Mitosis makes more cells than meiosis.
D) Mitosis makes more variety than meiosis.

Answers

Answer:

B

Explanation:

Mitosis has 1 meisosis has 2

Meiosis makes more cells than mitosis

Mitosis makes exact copies meisosis makes gentically differnt

A cell begins to produce a new type of protein. This is most likely due to an alteration of the 1 point structure of the cell membrane sequence of bases in a section of a chromosome chemical makeup of the cytoplasm shape of the antibodies produced by the nucleus

Answers

Answer:

The correct answer is - sequence of bases in a section of a chromosome

Explanation:

Protein synthesis is possible due to the nitrogenous base sequence of DNA molecules that acts as the template for the synthesis of the RNA molecule which moves to the cytoplasm and produces the Protein molecules from the sequence of mRNA that codes for specific amino acids according to the triplet codes.

So, the DNA or chromosomes are responsible for the synthesis of specific protein production and if there is any change in the sequence of bases in the DNA section it will lead to a new type of protein.

What happens to the number of chromosomes for species that go through sexual reproduction?

Answers

Answer:

In the first stage of sexual reproduction, "meiosis", "the number of chromosomes is reduced from a diploid number (2n) to a haploid number (n)" . During "fertilisation", haploid gametes come together to form a diploid zygote, and the original number of chromosomes is restored.

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What process do the animals (and plants) in the
rainforest use oxygen for?

Answers

Answer:

Animals and plants use oxygen for processing cellular respiration.

Explanation:

Most of all organisms use oxygen to undergo cellular respiration with the help of the mitochondria that powers energy. Cellular respiration is needed to obtain energy for survival. As products of cellular respiration, ATP energy is created, and carbon dioxide + water is released from the organism. Thus, an ecosystem like a rainforest with animals and plants use oxygen for processing cellular respiration.

If 5% of a DNA sample is made up of thymine, C, what percentage of the sample is made up of cytosine, A?

Answers

Answer:

95%

Explanation:

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