Numerous publications have reported successful outcomes of initial metatarsophalangeal joint bone block arthrodesis following a failed arthroplasty. After restoring an MTPJ arthrodesis with a bone graft, Myerson et al. found an increase of 40 points in pre and post-operative AOFAS scores (39 to 79).
Indications included unsuccessful arthrodesis surgeries with shortening of the first ray, Keller's procedures, several additional first metatarsal osteotomies, and failed hallux valgus surgery. Tricortical iliac crest grafts were placed in bone deficiencies with a mean length of 10.7 (range, 8-15) mm in all patients. Either numerous wires or a low-profile plate was used to achieve fixation. The average lengthening was 4.4 (from 0 to 8) mm. At the most recent checkup, two of the three feet had connected. Three feet continued to require more revision surgery. Every patient had their stabilizing Kirschner wire removed. Using the Foot and Ankle Disability Index, the median patient-reported outcome score was 84.6. (range, 37.5-97.1).
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You need to start an experiment and the instructions are to mix 2 g of sodium bicarbonate with 50 ml of distilled water and then mix the solution. Describe what lab apparatus you would use and what safety precautions you must observe when completing this experiment.
You need a weighing balance to weigh out 2g of solid sodium bicarbonate and a measuring cylinder to measure out 50 mL of water. You need to ensure that you use a facemask during the experiment.
How do we carry out the experiment?We know that we require apparatus to carry out a scientific experiment. The apparatus are those things that would help us to carry out the experiment that we want to do.
In this case, the activity is to mix 2 g of sodium bicarbonate with 50 ml of distilled water and then mix the solution. You need a weighing balance to weigh out 2g of solid sodium bicarbonate and a measuring cylinder to measure out 50 mL of water.
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pre-pro-insulin is a protein that is 110 amino acids long. how many peptide bonds are needed to make this protein?
Pre-pro-insulin is a protein that is 110 amino acids long. 250 peptide bonds are needed to make this protein.
What is Preproinsulin?Preproinsulin is used to start the manufacture of insulin in pancreatic beta cells. Prevalence glucose levels, which fluctuate pre- and post-prandially, have a significant dynamic effect on preproinsulin production. The endoplasmic reticulum (ER) translocation apparatus components linked to successful orientation of the signal peptide, translocation, and signal peptide cleavage of preproinsulin — all of which are required to start the pathway of proper proinsulin folding — accompany upregulated translation of the insulin precursor. It is remarkable that the efficiency of folding (or "foldability") of proinsulin has been retained due to evolutionary constraints on its basic structure, which are separate from those preserving the biological function of insulin.
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collagen is a protein made of three identical polypeptides composed primarily of α helix structure. the α helix is an example of a question 3 options: secondary structure stabilized by covalent bonds. tertiary structure stabilized by covalent bonds. tertiary structure stabilized by hydrogen bonds. secondary structure stabilized by hydrogen bonds. secondary structure stabilized by ionic bonds.
Collagen is a protein made of three identical polypeptides composed primarily of α helix structure. The α helix is an example of a (3) secondary structure stabilized by hydrogen bonds.
Collagen is a protein found in the human body in bones, tissues, skin, etc. It is very essential for the body as it increases the muscle mass, prevents the bone loss, relieves joint pain, and improves skin health. The most important properties of collagen are its rigidity and resistance to stretching.
Hydrogen bonds are the non-covalent bonds that are a most important part of various chemical structures. These are one of the strongest bonds. The hydrogen atom (electropositive) of one molecule is attached to the electronegative atom of the other molecule that could be fluorine, oxygen or nitrogen.
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long-term management of moderate-to-severe atopic dermatitis with dupilumab and concomitant topical corticosteroids
For a year, dupilumab was added to the usual topical corticosteroid regimen to ameliorate the signs and symptoms of atopic dermatitis while maintaining tolerable safety.
What is atopic dermatitis ?It's a chronic illness that occasionally flares up. The signs are diverse. Dr. Davis: Oval or circular patches of skin that are red, weepy, crusty, itchy, and flaky are typical of atopic dermatitis.
A combination of immune system activity, genetics, environmental factors, and stress contribute to the development of eczema (atopic dermatitis). your defence mechanism. Your immune system overreacts to minor irritants or allergens if you have eczema. This overreaction may cause skin inflammation.Learn more about Atopic dermatitis here:
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If it is 11pm, what would be the time for 20 hours before that.
Answer:
7 pm
Explanation:
Building a movie theater
What are 4 benefits and costs of building a theater?
Answer:
list six 6 types of network to pology and ex plain them.
after suffering a head injury, derick exhibits weak and uncoordinated movement of the jaw as well as numbness of the tongue and lower gums. which nerve was likely damaged?
Derick likely damaged the Trigeminal nerve after suffering a head injury since his symptoms are weak and uncoordinated movement of the jaw and numbness of the tongue and lower gums.
The trigeminal nerve is a part of the nervous system primarily responsible for sensing pain, touch and temperature in the face and sends the signal to the brain. The trigeminal nerve is the fifth of 12 cranial nerves and called the cranial nerve V.
There are two trigeminal nerves, one on each side of your body. They originate in the brain and travel throughout the head. The trigeminal nerve has three branches that perform various functions:
• Ophthalmic – related to forehead, eye and upper eyelids sends nerve impulses from the upper part of the face and scalp to the brain.
• Maxillary – which refers to the upper jaw extends to the lower eyelids, nose, cheeks and upper lip and gums is responsible for sensations in the middle part of the face.
• Mandibular – or the lower jaw branch aids sensation to the lower part of the face, like the jaws, lower lip and gum. These nerves also have a motor function and help in biting, chewing and swallowing.
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In cell signaling, the ligand/first messenger or ligand determines the intracellular response. True or false?.
In cell signaling, the ligand/first messenger or ligand determines the intracellular response this statement is False.
The process through which a cell reacts to things outside of it via signaling molecules that are both inside and on its surface is called cell signaling.
A cell can signal another cell or itself by releasing a chemical messenger called a ligand. The binding has biological effects that can take many different forms, such as affecting gene transcription or translation or modifying cell shape.
Extracellular signaling molecules like hormones or neurotransmitters, which bind to cell-surface receptors and activate intracellular signaling pathways, are the first messengers. These molecules rely on second messengers to spread and amplify the signal within the cell because they are unable to physically cross the cell membrane.
While most pathways share the same basic steps of cell signaling (reception, transduction, response, resetting), there are different pathways.
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how does dna (deoxyribonucleic acid) encode information? vhow does dna (deoxyribonucleic acid) encode information? information is encoded in the number of each different nucleotide. information is encoded in the sequence of nucleotides. the genes along the length of dna molecules encode the information for building all the cell's other molecules. the dna molecule is composed of many amino acids joined together to form a functional protein. information is encoded in the different shapes of the dna molecules.
DNA (deoxyribonucleic acid) is a double helix molecule that encodes information in the sequence of nucleotides.
What is deoxyribonucleic acid?DNA (deoxyribonucleic acid) is the molecule that serves to store the genetic material that will be transmitted across generations, this molecule is a double helix composed of long chains of nucleotides.
The nucleotide sequence of a single strand of DNA stores key information to synthesize proteins, which is achieved by sequential cell processes of transcription and translation.
In conclusion, DNA (deoxyribonucleic acid) is a double helix molecule that encodes information in the sequence of nucleotides.
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insulin signaling results in an increased transport of into cells, which allows the cell to subsequently increase synthesis and store energy in the form of in the liver and in the adipose.
The insulin signaling results in an increased transport of Glucose into cells, which allows the cell to subsequently increase synthesis and store energy in the form of Glycogen in the liver and in the adipose.
Glucose- Because glucose is a monosaccharide with six carbon atoms and an aldehyde group, it is an aldohexose. Glucose is the main sugar found in your blood. It comes from the food we eat and is used by the body as its main source of energy.
Glycogen- Glycogen is the name given to this type of glucose that is stored and is composed of several linked glucose molecules.
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oxidative stress with an activation of the renin–angiotensin system in human vascular endothelial cells as a novel mechanism of uric acid-induced endothelial dysfunction. j hypertens
A unique mechanism of uric acid-induced endothelial dysfunction, neighborhood stimulation of oxidative strain, and the renin-angiotensin system treat uric acid-brought about growing old and demise of human endothelial cells.
remedies that focus on uric acid can be wonderful for cardiovascular sickness.
HUVECs uncovered to uric acid at concentrations extra than 6 and 9 mg/dl, respectively, experienced senescence and apoptosis. Probenecid, enalaprilat, or telmisartan avoided modifications in mobile proliferation, senescence, and apoptosis introduced on by way of uric acid. starting at five min, uric acid dramatically accelerated the formation of reactive oxygen species, and N-acetylcysteine or tempol was capable of counteract uric acid-brought about senescence and loss of life in HUVECs. Tempol was effective in reducing the consequences of uric acid on angiotensin II degrees and upregulating the expression of angiotensinogen, angiotensin-converting enzyme, and angiotensin II receptors.To learn more about uric acid here:-
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a challenge to traditional (pre-1860) ideas about species came from embryology, when it was discovered that
a challenge to traditional (pre-1860) ideas about species came from embryology, when it was discovered that embryos of dissimilar organisms are also having similar embryonic structure.
Species is a group of organisms that can interbreed among themselves to produce viably offspring. Intially organisms with similar external features were considered to be related species. For example birds and bats, whale and shark.
But later on with the development of concept of embryology we were clearly able to identify organism who are different structurally but have evolved from a common ancestors. As whales are morphologically similar to sharks but they are considered mammals rather fish. similarly bats are also mammals and not aves.
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what is another function of the kidneys? to regulate the amount of sodium and potassium in the body to regulate the amount of sodium and potassium in the body to regulate growth of the reproductive system to regulate growth of the reproductive system to absorb glucose into the bloodstream to absorb glucose into the bloodstream to produce bile to digest food
Option A: The other function of the kidneys is to regulate the amount of sodium and potassium in the body.
The two bean-shaped organs, are equal to the size of your fist and are located just below the rib cage, one on each side are referred to as kidneys. kidneys are the primary organs of excretory system involved in the excretion process.
The main function of the kidneys is to filter blood by removing extra water from the blood. Apart from this kidneys also regulate the amount of salt and minerals such as - sodium, potassium, calcium, and phosphorus in the blood because without the balance and regulation of the minerals the nerves, cells, and tissues of our body may not work normally. The kidney also produces hormones that help:-
Control blood pressure
Regulate RBC production
Keep bones strong and healthy by producing Vitamin D
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neandertals’ cold-adapted traits include group of answer choices a projecting midface. long limbs. a narrow nasal aperture. a thin torso.
Neandertals’ cold-adapted traits include a narrow nasal aperture. The correct option is C.
Who are Neandertals?Neanderthals are extinct archaic human species that lived in Eurasia until about 40,000 years ago.
Homo sapiens has a high and rounded braincase as well as a relatively narrow pelvis.
Our braincase and pelvic shape can reliably distinguish us from Neanderthals, whose fossils show a longer, lower skull and a wider pelvis.
Cold-adapted characteristics of Neandertals include a narrow nasal aperture.
Thus, the correct option is C.
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during the surgical count before closure of the peritoneum, the scrub person and the rn circulator are unable to locate a laparotomy sponge. what is the first responsibility of the surgeon?
The first responsibility of the surgeon is notify the surgeon and go over the preoperative skin antiseptic choice.
Preoperative Skin- An excellent way to reduce surgery site infections is preoperative skin preparation (SSI). The two most often used antiseptics are povidone iodine (PV-I) and alcoholic chlorhexidine (CHG). Their effectiveness in lowering the normal bacterial skin flora after clean orthopedic surgery is the focus of this meta-analysis.
Antiseptic- An antiseptic is a chemical that prevents or slows the growth of microbes on the outside of the body, aiding in disease prevention.
Microorganism- A living thing that can only be observed under a microscope. Protozoa, algae, fungus, and bacteria are all examples of microorganisms.
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How does cell differentiation lead to the organization within a multicellular organism.
Cells eventually become specialized and use different parts of genes to become programme to do special jobs and look certain away.
What effects does an organism's cell differentiation have?The process of cell differentiation is crucial for complex creatures during all stages of their life, but it is especially crucial during embryonic development. This is as a result of the changes it brings about in the size, shape, metabolic processes, and signal responsiveness of cells.
Differentiated cells are important in a multicellular organism because they are able to perform a specialised function in the body.
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li, l. et al. the flavivirus precursor membrane-envelope protein complex: structure and maturation. science (80-. ). 319, 1830–1834 (2008)
Numerous viruses go through the maturation step before being transmitted to another host final stages of assembly.
Flaviviruses are a bunch of enveloped positive-stranded RNA viruses accountable for notable mortality and morbidity throughout the world. Flaviviruses fuse with the endosomal membranes of the prey cell in a pH-dependent fashion by entering cells via a clathrin-dependent endocytic pathway. Flaviviruses derived from the endoplasmic reticulum assemble at bud into membranes as immature virions on which E and prM proteins interact as heterotrimeric spikes.
The flaviviruses maturation process is staged by the proteolytic cleavage of the precursor membrane protein into shifting to infectious particles from the inert virus. The peptide β-barrel structure consists of the fusion loop in E, controlling fusion with host cell membranes. during maturation, The structure helps to identify the stages of the pH-directed conformational metamorphosis and leads to the release of pr when budding from the host.
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Fill in the missing levels of organization in living things from smallest to largest: cell, __________, organ, _______________, organism
The appropriate response is -.
1. Tissue
2. Organ system
The complexity of life has evolved from simplicity, as seen by the organization of living things.
A cell, which is thought of as the smallest unit of life, is what makes up a living thing. The cell gathers and organizes to form tissues that carry out comparable functions. The organs that are created from this tissue are specialized to carry out coordinated duties. The organ system that results from this specialization creates an organism.
Therefore, molecule, cell, tissue, organ, organ system, organism, population, community, ecosystem, and biosphere are the levels, going from smallest to largest.
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Every September, monarch butterflies migrate to Mexico by the millions. They stay there for the winter. They live in the branches of fir trees. Tall trees keep the butterflies safe from the rain. Trees also help to block the dangerous cold night air. Scientists are worried about monarch butterflies. The winter of 2010 was very troubling. There were fewer butterflies in Mexico that winter. In fact, it was the smallest population since 1993. Scientists think that they know why. Many fir trees are being cut down in Mexico. Without enough trees, the butterflies cannot survive.
Do It!
The butterflies use the trees for _________.
Press enter to interact with the item, and press tab button or down arrow until reaching the Submit button once the item is selected
A directions
B closets
C shelter
D food
The butterflies use the trees for shelter and is therefore denoted as option C.
What is Shelter?This is referred to as a structure or place which offers protection to different types of organisms and examples include burrows, tree branches etc. This helps to shield them from the harsh climatic conditions or from predators.
Organisms such as butterflies use tree branches as shelter from the harsh climate during winter because the leaves form a canopy hence protecting them in this scenario.
This is therefore the reason why there was a reduction in the population of the butterflies when the trees were cut.
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5. Select one organism that is a member of a Kingdom other than Animalia and give its
common name as well as its taxonomic classification (for example, corn is Kingdom-
Plantae, Phylum- Magnoliophyta, Class- Liliopsida, Order- Cyperales, Family- Poaceae,
Genus-Zea, Species- mays)
Taxonomy is the study and classification of organisms into different cathegories. Domain: Eukarya, Kingdom: Plantae, Phylum: Spermatophyta, Class: Dicotyledonae, Order: Rosales, Family: Rosaceae, Genus: Rose, Species: multiflora Thunb
What is taxonomy?
Taxonomy is the study of different organisms and their classification into categories according to
their morphologytheir molecular characteristics their evolutionary relationships.Based of these charactereistics, each organism gets a binomial name.
The categories in which organisms are classified are:
Domains are the highest taxonomic category in which living beings can be grouped or divided. There are three domains: archaea, bacteria, and eukarya.- The archaea domain
- The bacteria domain
- The eukarya domain
Kingdom Includes different phyla closely relates.- The bacteria domain includes the Eubacteria kingdom.
- The archaea domain includes the archaebacteria kingdom.
- The eukarya domain is divided into four kingdoms: Protist, Fungi, Plantae, and Animalia.
Phylum Include different classes closely related.Classes Include different orders closely relates.Orders Include different families closely relatedFamily Include different genera closely relatesGenus Include many species.Species might include subspecies.
For instanse, I chose a rose species
Domain ⇒ Eukarya,Kingdom ⇒ Plantae, Phylum ⇒ Spermatophyta, Subphylum ⇒ AngiospermaeClass ⇒ Dicotyledonae, Order ⇒ Rosales, Family ⇒ Rosaceae,Genus ⇒ Rose, Species ⇒ multiflora ThunbBINOMIAL NAME: Rosa multiflora Thunb.
COMMON NAME: Multiflora rose
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The flow of carbon from the biosphere to the atmosphere would be slowed by reducing the.
if phosphorous concentrations were to suddenly increase in a marine ecosystem, which of the choices would likely occur? decreased primary productivity no change in the rate of primary productivity increased primary productivity
If phosphorous concentrations were to suddenly increase in a marine ecosystem it will lead to increased primary productivity.
Phosphorus has a very important role in the growth, maintenance and repair of the living organisms. It plays a key role in how the organisms uses carbohydrates and fats . In human and other animals it also have a role in the formation of bones and teeth.
It is usually considered as a limiting nutrients in marine ecosystem as they don't have access to adequate amount of phosphorus for the growth and repair.
If the concentration of the phosphorus is suddenly increased the primary productivity of the marine system is also going to increase.
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The film defines species as populations whose members don’t interbreed. What keeps different galápagos finch species from mating?.
Answer:
Explanation:
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Answer:
Galapagos species are among those populations whose members do not interbreed. The reasons that keep them from mating is that they are separated due to differences in songs and beaks, individuals only recognize and respond to songs of their own species. Therefore, geographic isolation and different environments led to changes in traits that affected mating.
regulatory small rnas circumvent the conventional quorum sensing pathway in pandemic vibrio cholerae
Bacteria communicate with molecules of extracellular signaling known as autoinducers through a process called quorum sensing (QS) (AIs). Bacteria are able to coordinate gene expression on a population-wide scale in response to AIs, mimicking multicellular animals in certain ways. A phosphorelay circuit that interferes with the production of numerous short regulatory RNAs is used internally by Vibrio cholera EI Tor, the causative agent of the current cholera pandemic, to transduce AI information (sRNAs). The mRNA encodes the principal transcriptional regulator HapR and these RNAs form a base pair and inhibit translation of each other.HapR regulates the expression of virulence factors and the development of biofilms in V. cholera. Here, we uncover a QS mechanism that is sRNA-dependent but HapR-independent. In this system, the sRNAs base-pair with a new target mRNA to activate translation by avoiding the creation of a stem-loop structure, which inhibits translation. We demonstrate that the conventional V. cholera strain, which purportedly lacks QS due to a non-functioning HapR and produced prior pandemics, nevertheless demonstrates QS-controlled gene expression via this novel HapR-independent mechanism.
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answer all questions please
also quick please
Why do crickets chirp at higher temperatures?
Answer:
The reason that crickets chirp faster when it's warmer has to do with muscle contractions.
biology answers many questions, but its main focus is (5 points) a the animals of the earth and their environment b the history of life on earth c how people and animals interact and live d how living organisms interact and function
The right answer is D, how living organisms interact and function.
Because it focuses on the interactions of all living organisms, biology is crucial to study.
Describe biology.Biology is a branch of science that investigates how living things function.
Biology includes several different subfields, including botany, ecology, evolution, genetics, marine biology, medicine, microbiology, molecular biology, physiology, and zoology.
Basically, biology is the branch of natural science that concentrates on the study of life and living things. Without biology, comprehending the anatomy of humans, animals, and other species would be difficult.
Known as the "Father of Biology," Aristotle is "The Father of Zoology" is another name for him. He started classifying the kingdoms of animals and plants.
Aristotle's theory of biology, known as "Aristotle's Biology," explains metabolism, temperature control, and embryogenesis.
Biology is significant because it studies how all living things interact.
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Answer:
The right answer is D, how living organisms interact and function.
Explanation:
i got it right on the test
in a study on germination of radish seeds, five beakers were set up containing equal numbers of seeds. the beakers
Five beakers with equal numbers of seeds each were set up for a study on the germination of radish seeds. The conditions listed in the table below were applied to the beakers.
Which of the following pairs of beakers' data should be compared in order to identify whether or not enzymes are required for germination?
We will learn about the importance of enzymes for germination from beakers 1 and 2. Hence, option A: beaker 1 and 2 is correct.
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A person sweating to cool off is demonstrating what characteristic of life? A)gathering and using energy
B) growth
C) having DNA
D) maintaining homeostasis
Answer: i think its D)maintaining homeostasis
Explanation:
is a mathematical modeling approach to predicting the outcome of natural selection on behaviors when multiple organisms are interacting.
Evolutionary game theory is a mathematical modeling approach to predicting the outcome of natural selection on behaviours when multiple organisms are interacting.
What is natural selection?According to modern concept of evolution natural selection is not a bloody battle as was emphasized by Darwin and Wallace.
It is a peaceful process that has little to do with, "struggle for existence" or "elimination of unfit" or "survival of the fittest".
Natural selection really means differential reproduction ( some members of the population produce lage no of offspring, some are few and still others none.
Those that produce large no of offspring contribute greater percentage of genes to the gene pool of the next generation than those that produce fewer offspring.
If differential reproduction continues for many generation ,then genes of the individual which produce more offspring will become predominant in the gene pool of the population.
This leads to change in the gene frequency of the population.
Individual which are best adopted to the environment having greater no of surviving ones.
Survival of the organism to the reproductive age and their selection for mating is the important factors which results in differential reproduction.
There are three types of natural selection stabilizing
selection, directional selection and disruptive selection.
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