Why is retinoblastoma more common in individuals who have inherited the RB deletion and have the genetic predisposition for retinoblastoma?

Answers

Answer 1

Answer:

Retinoblastoma is more common in people due to the mutation of RB gene in them.

Explanation:

Retinoblastoma is a disease that affects the eyes of an individual. It is more commonly eye cancer which occurs on the retina of the eye. Retinoblastoma mainly affects younger children.

When the RB gene is mutated or it is deleted already on any one of a homologous chromosomes, then only one hit rather that two which is needed to cause the development of retinoblastoma and hence the probability is of retinoblastoma to occur is higher in the individuals who have already inherited the RB deletion and also have a genetic predisposition for the retinoblastoma.


Related Questions

compare and contrast prokaryotic vs eukaryotic

Answers

Answer:

prokararyotic: organisms whose cells lack a nucleus and other organelles

two distinct groups: the bacteria and the archaea

eukaryotic: organisms whose cells contain a nucleus and other membrane-bound organelles

animals, plants, fungi, and protists, as well as most algae

single cell or multicellular

eukaryotic cells have a distinct nucleus containing the cell's genetic material, while prokaryotic cells don't have a nucleus and have free-floating genetic material instead

Explanation:

Answer:

Prokaryotic cells lack a nucleus and are usually bacterial while eukaryotic cells have a nucleus, and chromosomes. On the other hand, prokaryotes have chromosomes but they are different, so they do not classify as chromosomes.

Hope this helps, leave a thanks if it did and have a good day!

Which system is responsible for the force that moves blood throughout body?

Answers

Answer:

circulatory system

Explanation:

What a person _____ become is determined by genetics, but what he or she _____ become often depends on the environment.
can; might
will not; will
can; does
does; can

Answers

What a person can become is determined by genetics, but what he or she might become often depends on the environment

1. The mechanism of breathing – how do inhalation and exhalation actually occur.

Answers

When the air pressure within the alveolar spaces falls below atmospheric pressure, air enters the lungs (inspiration), provided the larynx is open; when the air pressure within the alveoli exceeds atmospheric pressure, air is blown from the lungs (expiration).

Does the price change if you “bundle”
your insurance?

Answers

Answer:

yeah it does i think

blood type B
multiple choice
can donate to AB and B
has anti-B antibodies
has anti-A antibodies
can't have blood type A transfusion

Answers

Answer:

Has anti-A antibodies

Explanation:

This is because the liquid, a part of your blood while not cells (serum) is mixed with blood that's defined to be blood type and type B. individuals with type A blood have anti-B antibodies. people with type B blood have anti-A antibodies.

Hope it helps!


What is the difference between sickle-
cell amino acid sequence and normal amino
acid sequence?

Answers

There is a single cell substitution in the 4th amino acid in the sequence. glutamic acid is replaced by valine in the sickle cell sequence

Which of the following is NOT a reason for asexual reproduction in somatic cells? A growth B replacement of dead cells С repair injuries D to make gametes

Answers

Answer:

D. Making gametes technically isnt asexual reproduction because the offspring arent exact copies.

Explanation:

Mitosis is what replaces dead/ dying cells and repair injuries

We use heat and additional bacteria to make a cheesefrom yoghurt.
Do you think the heat can kill the bacteria ?
If you say Yes why we need to use bacteria?
If you say No why not the bacteria can kill us when we feed it?

Answers

bacteria are rapidly killed at temperatures above 149°F (65°C). we need to use bacteria because We could not survive without all the bacteria living on and inside us. They act as part of our immune systems, digest foods such as dairy that we cannot break down ourselves and provide us with nutrients and minerals that we need to survive.

Moving from the equator towards the poles allows you to cross through different ecosystems, which can also occur if?

A. You stay in one place through all 4 seasons
B. You use submarine
C. You cross from the western to eastern hemisphere
D. You climb a mountain

Answers

Answer:

C. You cross from the western to eastern hemisphere

Explanation:

I believe this is the most reasonable answer but the question is a little confusing. If it is asking how to travel through different ecosystems then C is the most reasonable as A would only change the temperature and sometimes change the weather. B would keep you underwater all the time and you can't really switch ecosystems unless you got out. D, your staying in one ecosystem when climbing a mountain.

Hope this helps :)

which of the following is not likely to be found at or occur at the boundary shown in the diagram below

Answers

Of the following items that are not likely to be found or will occur at the boundary shown in the diagram below is subduction

subduction

What is subduction?

  A subduction zone is a point where two of the planet's tectonic plates collide and one dips, or subducts, below the other, according to the National Oceanic and Atmospheric Administration (NOAA). This tectonic process can produce some of the most powerful earthquakes, tsunamis and volcanoes on the planet.

Learn more about subduction zone in brainly.com/question/13788626  

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Describe the structure of the cell membrane.

Answers

Answer:

The plasma membrane is composed of a bilayer of phospholipids, with their hydrophobic, fatty acid tails in contact with each other. ... Carbohydrates are attached to some of the proteins and lipids on the outward-facing surface of the membrane. These form complexes that function to identify the cell to other cells.

Explanation:

The top physical layer of the Earth is called

Answers

Answer:

lithosphere

Explanation:

I hope l helped you ❤❤

what is mutation? why are mutations more serious when they occur in a sex cell?​

Answers

Answer:

A mutation is the changing of the structure of a gene, resulting in a variant form that may be transmitted to subsequent generations, caused by the alteration of single base units in DNA, or the deletion, insertion, or rearrangement of larger sections of genes or chromosomes. Mutations in sex cells are more serious because they are heritable and affect the next generation.

Explanation:

giving brainliest!!

What charges are needed in the objects in order for attraction to occur?

A) A positive charge
B) A negative charge
C) A positive charge and uncharged
D) A negative charge and uncharged

Answers

Answer:

The balloon would likely become charged and its charge would exert a strange influence upon other objects in its vicinity. If some small bits of paper were placed upon a table and the balloon were brought near and held above the paper bits, then the presence of the charged balloon might create a sufficient attraction for the paper bits to raise them off the table. This influence - known as an electric force - occurs even when the charged balloon is held some distance away from the paper bits. The electric force is a non-contact force. Any charged object can exert this force upon other objects - both charged and uncharged objects.

Explanation:

Answer:

I think it’s C because positive charge and uncharge can attract each other

It can’t be D because none of the photos have a negative charge

Without evaporation, the water cycle would not be able to continue to repeat over and over again.


TRUE OR FALSE QUESTION

Answers

True

Evaporation is one of the key parts of the water cycle

Which statement is an example of cell division at work?

A tree grows taller.


A dog digests food.


A plant dies.


A muscle contracts.

Answers

Answer:

Hi there~

The answer would be:

A. A tree grows taller.

Hope this helps

Minisugarr

A tree grows taller.....

hope it helps you

When a hawk eats a mouse and then uses the energy from the mouse to fly,
the hawk's body converts to what

Answers

Answer:

It would be Chemical to mechanical

Explanation:

Because food is a chemical source and the hawk flying is a mechanical source.

When a hawk eats a mouse and then uses the energy from the mouse to fly in this case chemical energy is converted to mechanical energy.

What is food chain?

Food chain is the sequence of flow of energy in which all the levels get proper food supply and it is the food web which starts from producer and ending at top such as predator species, decomposer and detritivores.

In food chain plants play the role of producers as they are autotrophs and they prepare their own food in the presence of sunlight and all other organisms depend upon plant for food so they are known as producers in the food chain.

The main role of food chain is to understand the importance of each organisms and how they are depend on each other as well as to understand the role of food chain in maintaining ecological balance.

Therefore, When a hawk eats a mouse and then uses the energy from the mouse to fly in this case chemical energy is converted to mechanical energy.

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Approximately how many total ATP equivalents are generated by the complete oxidation of one molecule of acetyl CoA via the citric acid cycle?a) 1.5b) 2.5
c) 10
d) 30

Answers

Answer:

C. 10 ATP molecules

Explanation:

In the citric acid cycle is a series of eight reactions steps in which a two-carbon molecule, acetyl-CoA, enters the cycle through citrate and two atoms of carbon are removed as two molecules of carbon dioxide.

The energy generated by the complete oxidation of one molecule of acetyl CoA via the citric acid cycle is conserved in the production of three NADH molecules, one FADH₂ and one ATP molecule. Each NADH molecule transfers two electrons to oxygen in the electron transport chain, forming 2.5 ATP molecules each in the process. Similarly, an FADH2 molecules transfers two electrons to oxygen in the electron transport chain yielding 1.5 ATP molecules.

Total ATP molecules produced:

3 NADH + 1 FADH2 + 1 ATP = (2.5 × 3) + (1.5 × 1) + 1 ATP = 10 ATP  molecules

Therefore, 10 ATP molecules are generated by the complete oxidation of one molecule of acetyl CoA via the citric acid cycle.

Trace the path of nitrogen from atmospheric N2 into glutamate. Name the enzymes, substrates, products, and coenzymes.

Answers

Answer:

The path of the atmospheric nitrogen to the glutamate involves three broad steps where it is fixed to ammonia which is incorporated into glutamine and then finally forms glutamate by catalyzation reaction. These three reactions are given below with products formed, reactants, and enzymes involved:

1. Atmospheric nitrogen is the reactant that is reduced to ammonia (product) in this reaction. This reaction is catalyzed by the nitrogenase complex present in bacteria present in legumes:

N2 + 10H+ + 8e- + 16ATP → 2NH4+ + 16ADP + 16Pi + H2.

2. Ammonia (reactant) is incorporated into glutamine (product) in this second reaction which involves glutamine synthetase as catalyst: Glutamate + NH4+ + ATP → glutamine + ADP + Pi + H+.

3. Finally glutamine (final product) is formed by the glutamine (substrate) catalyzed by the glutamate synthase

α-Ketoglutarate + glutamine + NADPH + H+ → 2 glutamate + NADP+.

Solution :

Firstly the nitrogen molecule, [tex]$N_2 $[/tex] is reduced to to [tex]$NH_3$[/tex] (ammonia) in the reaction that is catalyzed by nitrogenase complex. It is present in the certain prokaryotes, which includes some of the live symbiotically with the legumes

[tex]$N_2 + 10H^ + + 8e^- + 14 \ ATP \rightarrow 2NH_4^+ + 16ADP + 16Pi + H_2$[/tex]

The ammonia is then incorporated into the glutamine in reaction that is catalyzed by the glutamine synthetase:

[tex]$\text{glutamate} + NH_4^+ + ATP \rightarrow \text{ glutamine} \ + ADP + Pi + H^+$[/tex]

And finally the glutamate synthase that catalyzes the formation of the glutamate from the glutamine :

α-Ketoglutarate + glutamine + NADPH + [tex]$H^+ \rightarrow 2 \ glutamate + NADP^+ $[/tex]

Also there is an alternative minor route for the formation of glutamate from ammonia that involves reaction catalyzed bu the glutamate dehydrogenase :

[tex]$\alpha - \text{Ketoglutarate} + NH_4^+ + NADPH \rightarrow \text{ glutamate} \ NADP^+ + H_2O $[/tex]

The law of_____
is the law describing how factors
for the same trait go to different gametes.

The answers or on the photo

Answers

Answer:

The correct answer is - segregation.

Explanation:

The law of segregation states that out of two factors or alleles of a gene located in an organism, only one allele or factor is distributed to each sperm cell or egg cell (gamete) randomly, So, the segregation of the alleles are random and only one allele is distributed to each gamete according to this law.

The law of segregation helps in making a different combination of alleles in a particular species or population and leads to variation in genetics. It makes sure that traits distribute to each generation randomly.

Meiosis makes sperm and egg cells. In humans, sperm and egg cells each have
_____ chromosomes. Therefore, a fertilized human egg cell (sperm and egg cell combined)
would create a cell with ____ chromosomes.

Answers

Answer:a sperm or a egg has an average of 11 chromosomes. both sperm and egg combine together would create 22 chromosomes. the average number of a normal human cell.

Explanation:

Answer:

13 chromosomes, 26 chromosomes

Explanation:

A plate moving at a rate of 4 cm/year is moving toward a plate that is 10,000 km away. In how many years will the plates collide?

250 million years
2,500 years
25 thousand years
250,000 years

Answers

Answer:

250 million years

Explanation:

I did the test

Answer:

250 million yrs

Explanation:

trust me slime

A plant reproduces by making sperm through mitosis, and the plant is haploid. It is?

A. A saprophyte
B. A gametophyte
C. A sporophyte
D. A neophyte

Answers

Answer:

the answer would just have to be c

Suzanne drew a diagram to compare the functions of roots and leaves. Which characteristic belongs in the area marked Y?

- anchors plant
- stores food
- absorbs minerals
- produces glucose

Answers

Answer: absorbs minerals

Explanation:

Answer:

the dude above is right

Explanation:

The production of egg and sperm cells is necessary for sexual reproduction because —

A.it increases the number of chromosomes so that the gametes can combine, giving the organism a complete set of chromosomes
B.it reduces the number of chromosomes so the gametes can combine, giving the organism a complete set of chromosomes
C.it increases the number of developing offspring

D.it decreases the number of developing offspring

Answers

Answer:A.it increases the number of chromosomes so that the gametes can combine, giving the organism a complete set of chromosomes

Explanation:

Take the class last year

When there is the egg production so it increase the no of chromosomes where the gametes should combined.

What are chromosomes?

A chromosome refer to the long DNA molecule where it contain the genetic material with respect to the organism.

Mainly eukaryotic chromosomes involved the packaging proteins that we called as the histones that should be aided by the chaperone proteins.

Therefore, we can conclude that the correct option is a.

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What major factors play a role in global warming?

Answers

Answer:

1. Carbon dioxide levels in the Earth's atmosphere have been steadily increasing.

Explanation:

Natural factors and human activity are the major factors that play a role in global world. Hope this is right, if not sorry. Have a great day!

Which of the following can be true about invasive species?
B
Invasive species are not a a threat to new
environments.
А
Invasive species increase the biodiversity of an
ecosystem
с
Invasive species can help destroy other invasive
species in an ecosystem

Answers

Answer: invasive species don’t help each other

Explanation:

What's the interaction between pearlfish and sea cucumbers?
a) competition
b) predation
c) parasitism
d) mutualism
e) commensalism

Answers

Answer:

commensalism is the answer

E) Commensalism, the pearfish benefits from the Sea Cucumber.

Suppose a study is being conducted to understand the potential heritability of artistic ability. Specifically, the study wants to recruit pairs of monozygotic and dizygotic twins raised in the same or in different environments. For each scenario, what is the theoretical genetic variance and environmental variance?
1. Monozygotic in the same environment
2. Monozygotic in a different environment
3. Dizygotic in the same environment
4. Dizygotic in a different environment
Answer Bank
0% genetic variance, 100% environmental variance
0% genetic variance, 0% environmental variance
50% genetic variance, 100% environmental variance
50% genetic variance, 0% environmental variance
Using the data collected from the study, what equation could be used to estimate the degree of phenotypic variability of artistic ability that is due to genetic factors?
H² = 2(rmz-rpz), where H² is broad-sense heritability
h2 VA/VP, where h’ is narrow-sense heritability
h2 = 2b, where ha is narrow-sense heritability
Vp = VA + VD + V1 + VE + VGE, where Vp is phenotypic variance

Answers

Answer:

Explanation:

Monozygotic in the same environment

Genetic Variance will be zero and the environmental variance will be zero this is because a monozygotic twin shares the same gene 100% and because they stay in the same environment they are equally exposed to the same thing this makes environmental variance Zero.

Monozygotic in a different environment

Monozygotic in different environment will have an environmental variance 100% this is because they are expose to different environment leading to variation in what they know and 0% genetic variance

Dizygotic in the same environment

They have 0% environmental variation and 50% genetic variation this is because they are fraternal twins and not 100% genetically only 50% of their traits are identical

Dizygotic in a different environment

They will have 100% environmental variance because they are raised in different envrionment leading to variation in idea and what they know and 50% genetic variance because Dizygotic twin are not genetically identical.

The formula to calculate phenotypic variance due to genetic variation is

Hb2 = 2(rmz - rdz) this is in accordance to falconer's formula for twin heritability and its estimatebroad sense heritage.

Where hb2 is broad sense heritability

Genetic and environmental variance determine the phenotypic variability among individuals. 1) b / 2) a / 3) d / 4) c. The equation h² = VA/VP could be used to estimate the degree of phenotypic variability due to genetic factors.

                 

------------------------

1. Monozygotic in the same environment ⇒ 0% genetic variance, 0% environmental variance

Monozygotic twins have no genotypic variation, they share the genotypic charge, meaning there is no difference between them.

Since they grow in the exact same environment, they are exposed to the same factors and, hence, they express no difference.

2. Monozygotic in a different environment ⇒ 0% genetic variance, 100% environmental variance

Monozygotic twins have no genotypic variation, they share the genotypic charge, meaning there is no difference between them.

However, since they were exposed to different environmental factors, they express differences that are due to external elements or conditions.

3. Dizygotic in the same environment ⇒ 50% genetic variance, 0% environmental variance

Part of the genetic charge might be different because they developed from different eggs. They are not identical twins, so they express genotypic variation.

Environmental factors do not play a significant role because twins were equally exposed to the same conditions, so there is no varying environmental influence.

4. Dizygotic in a different environment ⇒ 50% genetic variance, 100% environmental variance

Part of the genetic charge might be different because they developed from different eggs. They are not identical twins, so they express genotypic variation.

Besides, as twins grew in different environments, which means they also express phenotypic differences that are due to external elements or conditions.

Heritability in the narrow sense -h²- refers to the proportion of the phenotypic variability that is influenced by genetic factors.

Heritability in the narrow sense is the measure of the genetic component to which additive genetic variance contributes.

The heritability might be used to determine how the population will respond to the selection done.

The equation that could be used to estimate the degree of phenotypic variability of artistic ability that is due to genetic factors is

                  h² = VA/VP ⇒ where h’ is narrow-sense heritability

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