TP53 is a recessive gene and is not located on the X chromosome, why would people who inherit just one mutant copy of a recessive tumor-suppressor gene be at higher risk of developing cancer than those without the recessive gene?

Answers

Answer 1

Answer:

Explanation:

Since it is a recessive gene, tumor suppressor genes required the inactivation of both alleles, this is usually accomplished by the mutation of one allele and a targeted homozygous deletion of the second allele. This leads to an effective inactivation of the suppressor genes with the mutations acting a a dominant negatives. This way, patients are put at a higher risk of developing cancer


Related Questions

Where do sperm mature?
O A. Epididymis
O B. Urethra
O c. Seminiferous tubules
O D. Vas deferens

Answers

Answer:

A.

Explanation:

Sperm migrate from the seminiferous tubules to the epididymis.

the answer will be A
hope you get it right:))

which feature of a membrane describes wether molecules can cross the membrane​

Answers

Answer:

Permeability

Explanation:

Membranes are semi-permeable that only certain things can come cross on its own. This feature of permeability describes whether molecules can cross the membrane​

State three economic importance of mucor

Answers

Answer:

Mucor velutinosus and Mucor ellisoideus both infect humans. Mucor indicus is a mold that is actually economically valuable. It's used to produce ethanol, and has a large array of sugars it can use as a food source. Mucor indicus is also used as fish feed and may be a valuable tool to clean up oil spills.

hope it helps : D

Explanation:

The three economic importance of mucor are:

Production of industrial enzymesProduction of organic acidsBioremediation

Mucor species are used to produce a variety of industrial enzymes, including amylases, proteases, and lipases. These enzymes are used in a wide range of industries, including the food, beverage, and textile industries. Mucor species are also used to produce organic acids, such as citric acid, gluconic acid, and fumaric acid.

These acids are used in a variety of products, including soft drinks, pharmaceuticals, and food additives. Mucor species can be used to bioremediate contaminated soil and water. They can degrade a variety of pollutants, including petroleum hydrocarbons, pesticides, and heavy metals.

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Based on the objective you should feel comfortable calculating expected genotype frequencies when given observed allele frequencies. You should also be able to compare expected genotype frequencies from HWE to observed frequencies and determine if evolution is occurring.Here's a sample problem. You can do this without a calculator!Let's take the noob gene, a gene with two known alleles that determines feather color in the eastern lark. The two alleles, let's call them delta and gamma, can be sequenced. In fact, looking at a population in southern GA, you discover that 60% of the alleles in the population are the delta allele.1. What is the percentage of the gamma allele in the population?2. Even more interesting, based on HWE what is the expected frequency of the population that is homozygous gamma? 3. Now, after surveying an isolated population of eastern larks, you find that 20% of the population is homozygous gama (gamma gamma), 65% heterozygous (gamma delta) and 10% homozygous delta (delta delta) and 5% of the population is a previously undescribed genotype - zeta zeta (homozygous zeta). What can you conclude about evolution in the population and why? If evolution is occurring, which mechanism(s) would be responsible?

Answers

Answer and Explanation:

60% of the alleles in the population are the delta allele

1. What is the percentage of the gamma allele in the population?

According to Hardy-Weinberg, the allelic frequencies in a locus are represented as p and q, referring to the allelic dominant or recessive forms. The genotypic frequencies after one generation are p² (Homozygous dominant), 2pq (Heterozygous), q² (Homozygous recessive). Populations in H-W equilibrium will get the same allelic frequencies generation after generation. The sum of these allelic frequencies equals 1, this is p + q = 1.

In the same way, the sum of genotypic frequencies equals 1, this is

p² + 2pq + q² = 1

Being

p the dominant allelic frequency, q the recessive allelic frequency, p²the homozygous dominant genotypic frequency q² the homozygous recessive genotypic frequency 2pq the heterozygous genotypic frequency

According to the sum of the allelic frequencies

p + q = 1

1 equals 100%

100% ------ 1

60%------0.6

40%------0.4

The percentage of gamma allele in the population is 40%.

2. what is the expected frequency of the population that is homozygous gamma?

The genotypic frequencies, F, after one generation are p² (Homozygous dominant), 2pq (Heterozygous), q² (Homozygous recessive).

F(gamma)= p²= 0.4²=0.16 =16%

F(delta)= q²= 0.6²=0.36 = 36%

F (gamma-delta) = 2xp2q= 2 x 0.4 x 0.6 = 0.48 = 48%

3.  20% of the population is homozygous gama (gamma gamma), 65% heterozygous (gamma delta) and 10% homozygous delta (delta delta) and 5% of the population is a previously undescribed genotype - zeta zeta (homozygous zeta). What can you conclude about evolution in the population and why? If evolution is occurring, which mechanism(s) would be responsible?      

20% gamma-gamma

10% delta-delta    

65% gamma-delta  

5% zeta-zeta  

This population has different genotypic frequencies with respect to the population in southern GA:

The gamma genotypic frequency is a little bit higher in the isolated population (16% vs 20%)

The delta genotypic frequency is considerably lower in the isolated population (36% vs 10%)

The heterozygotic genotypic frequency is also higher in the isolated population (18% vs 64%)

It appeared a new phenotype in the isolated population, probably due to a mutation in one of the genes. We can assume that this is a new mutation because its frequency is still low (5%).

Maybe, the mutation occurred in an individual of the isolated population, and with time, this mutation increased its frequency, up to a point of being phenotypically visible. This could be a case of a bottleneck example.

The founder effect is a special case of genetic drift, where a few organisms of one population settles down in a new area carrying the genes of the original population.  

Genetic drift is the random change in the allelic frequency in a population, from one generation to the other. The magnitude of this change is inversely related to the size of the original population. These changes produced by genetic drift accumulate in time, and eventually, some alleles get lost, while some other might get set.      

Founder effect refers to the consequences that occur from the origin of a new population that derives from a small number of founder individuals that come from an ancestral bigger population. This small group shows poor genetic variation and a high possibility of expressing a peculiar allelic composition. Some mutation might occur and it can accumulate in time.

     

What type of molecules are antigens?

Answers

Antigens are usually proteins, peptides (amino acid chains) and polysaccharides (chains of monosaccharides/simple sugars) but lipids and nucleic acids become antigens only when combined with proteins and polysaccharides.

The color varieties of sunflower pollen are determined by two interacting loci: A_B_ gives orange pollen, aaB_ gives yellow, and _ _bb produces cream colored. Assume that two fully heterozygous plants are crossed. Give the phenotypes (with frequencies) of the offspring. What type of gene interaction would account for these results?

Answers

Answer:

This is an illustration of epistasis type of gene interaction.

Explanation:

On crossing AaBb * AaBb, the offspring produced are mentioned in the Punnett square given in the attachment below. Based on the Punnett square, the phenotypic ratio will be 9 (orange): 4 (cream) : 3 (yellow).  

The given case is an illustration of the epistasis kind of gene interaction. When two or more distinct gene loci take part in the formation of similar phenotype, however, not additively is termed as epistasis, that is, it is the non-allelic association between the alleles situated at a distinct gene locus. In the phenomenon of epistasis, one of the gene loci modifies or masks the phenotype of a second gene locus.  

Which of these conditions doesn’t not contribute to the weathering of rock on earth’s surface

Answers

Answer:

The correct answer is

C. Constant high pressure

Explanation:

Constant high pressure is not a factor that causes weathering on the earth surface.

Temperature, air and water affects how a rock changes through time. They have the capacity to cause physical disintegration and chemical decomposition of rocks.

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What does lung hyperinflation stimulate (write on both lines)​

Answers

Answer:

What does lung hyperinflation stimulate? ... Dust, smoke, and noxious fumes will stimulate receptors in airways.

Explanation:

please mark me as brainliest i hope this helped you... : D

Vhat do scientists need to look at before developing an argument?

The validity of data, claims, hypotheses, and observations.

Their opinion and personal views.

The arguments of famous people on the topic.

The arguments that make the most sense for society.

Answers

Answer:

The validity of data, claims, hypotheses, and observations.

Explanation:

Making an argument and discussion over the scientific arguments are considered important to the scientific method.

The argument should be made in a way that it should check the validity of the hypothesis. The scientist who has to make an argument should consider various steps of scientific method like hypothesis which should predict the explanation of the natural phenomenon.

The person should consider the validity of the data whether it supports the hypothesis or not and observation of the experiment.

Thus, the selected option is the correct answer.

Answer:

A

Explanation:

The validity of data, claims, hypotheses, and observations.

edge 2020

Your mother points out to you a magazine article that says better nutrition is the reason modern Americans are taller than Americans of two centuries ago. What is a valid statement that would contradict this?

Answers

Answer:

This is  true, because the advent of genetic engineering and different nutritional researches  have greatly enhanced  the Nutritional values in foods, with resultant increases in the growth and development of cells and tissues from increase growth hormones metabolism. However, reduction in the outbreak of disease, due to advancement in medical research and drug manufacturing are another factors which may contribute to this

Explanation:


Why are fats considered as high energy compounds?
What is the function of mRNA?
What is the general formula for amino acids?​

Answers

Answer:

1. Fats contain mostly C-H bonds, it has less oxygen therefore making it a high energy compound

2. mRNA plays a vital role in protein synthesis. It's a single stranded RNA molecule that contains genetic information that can be taken outside the nucleus (unlike DNA which cannot leave the nucleus). Its created during transcrption, and is used during translation to create proteins

3. (Look at image)

1. The organic molecules that contain esters of fatty acids and a mixture of compounds are called fats. They provide energy to the body for functioning. They provide slow energy but the most efficient energy.

The amount of calories supplied by fats is twice as compared to carbohydrates and proteins. The excess of fats is stored in the body for future purposes.

2. mRNA is a type of RNA and plays a vital role in the process of translation. It is a single-stranded molecule that contains genetic information transcripted from DNA and is transported out from the nucleus into the cytoplasm.

The main function of mRNA is in protein synthesis. It helps in the formation of amino acid sequence that undergoes modification to form proteins.

3. The general formula of amino acid is [tex]\rm R-CH(NH_{2})-COOH[/tex].

The side chains of different amino acids vary accordingly. The structure consists of a carboxylic group along with an amino group and an organic side chain.

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After a polypeptide chain has been synthesized, certain amino acids in the peptide may become modified. For each modified amino acid, identify the standard amino acid from which it is derived. Enter the unabbreviated name of the standard amino acid.

Answers

Answer:

Lysine

Explanation:

Lysine is a unabbreviated name of amino acid. It is used in biosynthesis of proteins. It contains [tex]\alpha[/tex]-amino group and [tex]\alpha[/tex]-carboxylic acid group which has formula is C6H14N2O2. Lysine is also considered as building block of amino acid. It is used for treating cold sores and can be applied directly to the skin.

Calculate the efficiency of glycolysis if 12 kcal of energy are required to transfer energy from glucose to ATP.
Explain please​

Answers

Answer:

The ATP has a full meaning . If you get to know the full meaning you will understand it

Viruses reproduce by .

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the virus attaches itself to the host cell and inserts it's genetic material into it. then the host cell spreads the viruses genetic material which will result in spreading the virus.

According to the calendar, it has been about 14 days since the beginning of the last lunar
cycle. Usually, the moon is bright white, but today a dark red moon hangs in the night sky.
What are you witnessing?
A. a northern light
B. a solar eclipse
C. a lunar perihelion
D. a lunar eclipse

Answers

D the lunar eclipse, im pretty sure is correct

Which describes a eukaryotic cell, but not a prokaryotic cell? a. uses DNA to control cell activities b. is surrounded by a cell membrane c. makes and uses proteins d. contains DNA in a nucleus

Answers

Answer: Eukaryotic cells are larger than prokaryotic cells and have a “true” nucleus, membrane-bound organelles, and rod-shaped chromosomes. The nucleus houses the cell's DNA and directs the synthesis of proteins and ribosomes.

So..the answer should be D. Eukaryotic cells have a true membrane-bound nucleus and prokaryotes do not

All cells have a plasma membrane, ribosomes, cytoplasm, and DNA. Prokaryotic cells lack a nucleus and membrane-bound structures. Eukaryotic cells have a nucleus and membrane-bound structures called organelles.

So..it can't be C. or A. or even B.

Correct me if I'm wrong.

Please help me!!!!!!!!!!

Answers

Answer:

A. making new molecules for growth

Explanation:

Explain the link between climate change and globalization.

Answers

Answer:

La globalización hace más vulnerable la economía al cambio climático. La susceptibilidad de la red económica global al estrés por calor de los trabajadores se ha duplicado en la última década, según concluye un nuevo estudio publicado en la revista 'Science Avances'

Explanation:

Consider an experiment where you digest a DNA molecule with restriction enzyme BclI. You resolve the products of the digest by gel electrophoresis. Then, you cut out each of the resulting two bands from the gel and sequence the DNA. The sequencing results return two DNA segments.
Segment 1
5′ CCGCGGT 3′
3′ GGCGCCACTAG 5′
Segment 2
5′ GATCAGGATCC 3′
3′ TCCTAGG 5′
1. What is the sequence of the BclI recognition site?
2. What type of ends do the products have?

Answers

Answer:

This BclI restriction enzyme recognizes and cut at T / CTAG nucleotide sequences.

Explanation:

5′ CCGCGGT 3′

3′ GGCGCCACTAG 5′

Segment 2

5′ GATCAGGATCC 3′

3′            TCCTAGG 5′

The BclI enzyme generates sticky ends, it means that the enzyme recognises and cuts nucleotide sequences without complementary bases, which also have weak hydrogen bonds. The sticky ends are then generated when an enzyme produces unpaired nucleotide ends. Nonetheless, restriction enzymes generally produce blunt ends, i.e., both strands cut at the same site.

List the functions of kinases and cyclins, and describe how they interact to cause cells to move through the cell cycle. Drag the terms on the left to the appropriate blanks on the right to complete the sentences.

Answers

The provided question is incomplete as drag and drop box or required image is not available, however, the correct image of drag drop box is attached with the answer:

Answer:

Kinases are catalysts or enzyme that regulates the organic action of proteins by adding phosphate groups and cause the conformation change to a dormant to a functioning type of the protein.

Cyclins bind to CDK or cyclin dependent kinases to regulate by switching on and off the progression of the cell through cell cycle. At the G2 mitosis border , a CDK 1 combines with another cyclin ( B) , phosphorylation (adding of phosphate group) occurs bringing about a series of changes in the nuclear membrane via cytoskeleton, caldesmon and histone H1.  CDK 4 binds to cyclin D , moving cells from G1 to S.

what is the job of the stomach, large intenstine, small intestine 60 points!!

Answers

Answer:

Stomach - The stomach is a hollow organ, or "container," that holds food while it is being mixed with stomach enzymes.

Large Intestine - The large intestine absorbs water and electrolytes, and produces and absorbs vitamins. It forms and propells feces toward the rectum for elimination.

Small Intestine - The small intestine breaks down food coming from the stomach and absorbs the nutrients from the food.

Sensory information from proprioceptors about joint and muscle positions are carried to the brain by the: Sensory information from proprioceptors about joint and muscle positions are carried to the brain by the: anterolateral system (spinothalamic tracts). vestibulospinal tract. reticulospinal tract. spinocerebellar tracts.

Answers

Answer:

Spinocerebellar tracts.

Explanation:

Spinocerebellar tracts are afferent neurons that transmit proprioceptive information from the peripheral nervous system ( muscles and joints propricetors) to the cerebellum. It originated from the spinal cord and end at the cerebellum. It carry unconscious proprioceptive sensory information from the muscles, organs to the cerebellum.

A reseacher was studying mutations in bacteria.he found that certain bacteria had changes in their dna that allowed them to be resistant to antibotics.this research is an example of. The mutation will lead to

Answers

Answer: 1.B). Evolution genetics.

2.C). Less Bacteria becoming resistant to the specific Antibiotics .

Explanation:

Evolution genetics is field of science, which includes study of genetic variations that lead to evolutionary changes in organisms. As some bacteria had changed their DNA that led to development of antibiotic resistance in them.

Due to antibiotic resistance, certain bacteria, in which changes in DNA take place, become resistant against some type of antibiotics and those antibiotics are no longer effective to prevent or kill them

Thus, the correct options to be filled in the blanks are option (B) and option (C).

Building large manufacturing facilities can affect
ecosystems by increasing the

Answers

Answer:demand for resources such as fossil fuels

Explanation:

Building large manufacturing facilities can affect ecosystems by increasing the demand for resources such as fossil fuels.

Thus, The breakdown of buried, carbon-based organisms that perished millions of years ago produces fossil fuels. They produce deposits rich in carbon, which are taken out and burned to provide energy.

They presently provide about 80% of the world's energy and are non-renewable. A vast array of items, including plastic and steel, are also produced using them. Coal, oil, and gas are the three forms of fossil fuels.

Global warming is mostly caused by emissions from fossil fuels, according to the Intergovernmental Panel on Climate Change (IPCC). 89% of the world's CO2 emissions in 2018 came from industry and fossil fuels.

Thus, Building large manufacturing facilities can affect ecosystems by increasing the demand for resources such as fossil fuels.

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_________15. Which one of the following feature is common in C3, C4 and CAM photosynthesis?
A. Fix CO2 twice in their cycle
B. Produce oxaloacetaate as their stable produce
C. Fixation of CO2 occurs by mesophyll cells
D. Their bundle sheath having chloroplast with no thylakoids

Answers

A. Fix CO2 twice in their cycle

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a particular gene can have two forms, called alleles. which statement best describes the difference between the dominant allele and the recessive allele?

(a)only the recessive allele is expressed when both alleles ate inherited.
(b)the recessive allele can be expressed only if it moves to a different chromosome.
(c)only the dominant allele is expressed when both alleles are inherited.
(d)the dominant allele can be expressed only if two homologous chromosomes have it.

Answers

Answer:

The answer is D I'm pretty sure

Arrange the followings so that they accurately display the anatomical terms from bottom to top in order of the deepest to most superficial.

a. hair shaft
b. hair bulb
c. dermal papilla
d. hair root
e. hair matrix

Answers

Answer:

The correct arrangement from starting with the one at the bottom and/or deepest to the most obvious to the eye is:

E) Hair Matrix (Deepest)

C) Dermal Papilla

B) Hair Bulb

D) Hair Root

A) Hair Shaft (Most superficial)

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The antibiotics tetracycline and erythromycin inhibit bacterial protein synthesis, but have no effect on proteins encoded by eukaryotic, nuclear genes. Conversely, the antibiotic cycloheximide inhibits protein synthesis of nuclear genes, but has no effect on protein synthesis in bacteria.

Select the statement that best describes the effect of a particular antibiotic on protein synthesis.

a. It cannot be determined because two of these antibiotics affect bacteria, and cells with mitochondria are eukaryotic.
b. Tetracycline treatment would inhibit mitochondrial protein synthesis, but not protein synthesis of nuclear genes.
c. Erythromycin treatment would inhibit protein synthesis from nuclear genes, but not from mitochondrial genes.
d. Cycloheximide treatment would inhibit expression of mitochondrial genes, but not expression of nuclear genes.
e. Tetracycline treatment would inhibit translation of nuclear genes, but not translation of mitochondrial genes.

Answers

Answer:

I think it might be A

Pigment of chicken feathers is regulated by two genes, the gene for feather pigment C, and a gene that inhibits pigment production, I. A mother chicken, who is heterozygous for gene C, and heterozygous for gene I, is crossed with a father chicken, who is homozygous recessive for the pigment gene, and heterozygous for gene.
1) What are the potential haplotypes of the gametes produced by the mother for these two genes?
2) What are the potential haplotypes of the gametes produced by the father for these two gametes?
3) What is the probability of one of the offspring of these two chickens having pigmented feathers?
4) In a population of 100 chickens, produced from the same parents, how many chickens would you expect to have white feathers?

Answers

Answer:

(1) CI Ci cI ci

(2) CI Ci

(3) 25

(4) 75

Explanation:

Mother is in this case is heterozygous for C & I, genotype of mother would be : CcIi

Father is on other hand is homozygous for C (dominant) and heterozygous for I, genotype : CCIi

1. Gametes produced by the mother will be:

 CI Ci cI ci  by the combinantion of C, I, c, and i alelles present in mothers genotype.

2. Gametes produced by the father :

CI Ci  by the combinantion of alleles present i genotype of father CCIi

3. probability of one of the offspring of these two chickens having pigmented feathers:

 2/8 × 100 = 25% ( punnet is attached)

4. chicken with white feather in population of 100 chickens:

 probability of being white ×  100

probability of being white : 1 - 2/8

thus, (1-2/8) × 100 = 6/8 × 100

    = 75%

Interplanetary material that enters the earths atmosphere and collides with the ground rather than burning up is called

Answers

Explanation:Meteorito o meteoro

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I need help. Like just help please lol I dont understand this and Im dumb :) thanks Of the reactions listed below, which one is NOT a combination reaction? A) C + O2 => CO2 B) 2Mg + O2 => 2MgO C) 2N2 + 3H => 2NH3 D) CaO + H2O => Ca(OH)2 E) 2CH4 + 4O2 => 2CO2 + 4H2O Which of the following is often found in individuals who are active and eating a healthy diet? DNA serves as a template for a new strand How much heat is added if 0.2067g of water is increased in temperature by 0.855degrees C? You have learned about several groups and individual warrior women in mythology and history. How do you believe that these stories might influence current women? Answer needs to be one paragraph long at least. Write p(x) = 21 + 24x + 6x2 in vertex form. Imagine that you have a 500 g iron pot (c = 0.440), a 500 g copper pot (c = 0.385), and a 500 g aluminum pot (c = 0.897). You fill each pot with 250 mL of water and heat the water to 100C on a stove. Which pot will keep the water warm the longest? Explain your answer. How are fossils formed?Please help me. A ball is thrown straight up with an initial velocity of 35.7 m/s. How long doesit take to hit the ground? Claim: The mean pulse rate (in beats per minute) of adult males is equal to 69.3 bpm. For a random sample of 140 adult males, the mean pulse rate is 69.8 bpm and the standard deviation is 11.2 bpm. Complete parts (a) and (b) below. a. Express the original claim in symbolic form._,_,bpm Can sedimentary rocks have layers? If so, how would they form? What comes after 2- on the number line Which can you use to evaluate and assess your writing? Divide x4 + 7 by x-3. Tristan is working two summer jobs, making $7 per hour babysitting and $19 per hour lifeguarding. Tristan must earn at least $210 this week. Write an inequality that would represent the possible values for the number of hours babysitting, bb, and the number of hours lifeguarding, ll, that Tristan can work in a given week. what is called periodic function give example? Plot the output which is started with zero degree for one coil rotating in the uniform magnetic field and name it. How can you represent this output as the periodic function? what are the steps I need to do to get the answer? 1. I watched TV ....... I went to bedlast night. a. Finally b. First c. Before d.next e.After f.after than 2. I caught the ball......he threwit to me.3. He saw the fire......he criedfor help.4. I got washed and dressed.....I went to work.5.she got on the plane and.......then she found her seat.7. They said, "Good-bye"......they left.8. I was late but......two hours !finally arrived at college.9. The little boy cried...... he felloff his bicycle.10.Tom opened the box.......and then he looked inside. Celine Dion Company issued $600,000 of 10%, 20-year bonds on January 1, 2017, at 102. Interest is payable semiannually on July 1 and January 1. Dion Company uses the straight-line method of amortization for bond premium or discount. Instructions Prepare the journal entries to record the following. A) The issuance of the bonds. B) The payment of interest and the related amortization on July 1, 2017. C) The accrual of interest and the related amortization on December 31, 2017.